General
Preferred name
RACLOPRIDE
Synonyms
S(+)-Raclopride L-tartrate ()
Meglitinides ()
Raclopride84225-95-6 ()
RACLOPRIDE C 11 ()
[3H]raclopride ()
(11c)-raclopride ()
Raclopride c-11 ()
P&D ID
PD002893
CAS
84225-95-6
97849-54-2
104953-11-9
Tags
drug candidate
natural product
drug
available
Drug indication
Psychotic disorder
Type-2 diabetes
Radioactive Agent
Drug Status
investigational
approved
Max Phase
Phase 1
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Selective P2Y12 antagonist (Tocris Bioactive Compound Library)
DESCRIPTION Potent, selective D2/D3 antagonist (Tocriscreen Plus)
DESCRIPTION Potent, selective D2/D3 antagonist (Tocriscreen Total)
DESCRIPTION Selective D2 dopamine receptor antagonist (LOPAC library)
Cell lines
0
Organisms
2
Compound Sets
22
Cayman Chemical Bioactives
17422
ChEMBL Drugs
CHEMBL8809
CHEMBL2104769
Concise Guide to Pharmacology 2017/18
3299
94
Concise Guide to Pharmacology 2019/20
3299
94
Concise Guide to Pharmacology 2021/22
3299
94
Concise Guide to Pharmacology 2023/24
3299
94
Drug Repurposing Hub
DrugBank
DB12518
DrugMAP
DM1OFHN
DrugMAP Approved Drugs
DM1OFHN
Guide to Pharmacology
3299
94
LOPAC library
MedChem Express Bioactive Compound Library
HY-103414
NIH Clinical Collections (NCC)
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
raclopride
Tocris Bioactive Compound Library
1810
Tocriscreen Plus
1810
Tocriscreen Total
External IDs
42
Properties
(calculated by RDKit )
Molecular Weight
346.09
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
5
Ring Count
2
Aromatic Ring Count
1
cLogP
2.92
TPSA
61.8
Fraction CSP3
0.53
Chiral centers
1.0
Largest ring
6.0
QED
0.86
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
7-TM Receptors
Selectivity
D2
Primary Target
Non-selective Dopamine
MOA
Antagonist
Dopamine D2 Antagonists
Dopamine D3 Antagonists
Dopamine Receptor antagonist
Member status
member
Target
DRD2, DRD3, HTR1A
Dopamine Receptor
Pathway
GPCR/G protein
Neuronal Signaling
Source data