General
Preferred name
RUFLOXACIN
Synonyms
MF-934 hydrochloride ()
rufloxacin monohydrochloride ()
Rufloxacin hydrochloride ()
MF 934 ()
Rufloxacino ()
NSC-759835 ()
Rufloxacine ()
Rufloxacin (hydrochloride) ()
P&D ID
PD002874
CAS
106017-08-7
101363-10-4
Tags
available
drug
Drug Status
approved
experimental
investigational
Max Phase
2.0
Drug indication
bacterial disease
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Rufloxacin is a fluoroquinolone antibacterial compound, with broad-spectrum activity against both Gram-positive and Gram-negative bacteria .
(GtoPdb)
DESCRIPTION
The hydrochloride salt form of rufloxacin, one of the fluoroquinolone antibiotics, shows broad spectrum antibioterial activity especially against gram negetive bacteria.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Rufloxacin hydrochloride (MF-934 hydrochloride) is a fluoroquinolone antibacterial that inhibits topoisomerase and B-cell differentiation in human mononuclear cells.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
17
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
48
Molecular Weight
363.11
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
2
cLogP
1.7
TPSA
65.78
Fraction CSP3
0.41
Chiral centers
0.0
Largest ring
6.0
QED
0.88
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Antibacterial
antibiotic
Bacterial
Indication
gram-negative bacterial infections
MOA
bacterial DNA gyrase inhibitor
Pathway
Microbiology/virology
Anti-infection
Solubility
DMSO: 50 mg/mL
Source data
