General
Preferred name
Secoisolariciresinol
Synonyms
(-)-Secoisolariciresinol ()
(+)-SECOISOLARICIRESINOL ()
P&D ID
PD002865
CAS
29388-59-8
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Drug indication
Breast cancer
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Secoisolariciresinol is a lignan, a type of phenylpropanoids.
PRICE
389
DESCRIPTION
Secoisolariciresinol is an enterolignan precursor, it has antioxidant, and estrogen-like activities, it can significantly suppress triglyceride (TG) accumulation in 3T3-L1 adipocytes.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
3
Organisms
0
Compound Sets
7
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
MedChem Express Bioactive Compound Library
NIH Clinical Collections (NCC)
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
37
Molecular Weight
362.17
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
4
Rotatable Bonds
9
Ring Count
2
Aromatic Ring Count
2
cLogP
2.12
TPSA
99.38
Fraction CSP3
0.4
Chiral centers
2.0
Largest ring
6.0
QED
0.55
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
TNF-α
Drug intermediate
Pathway
Apoptosis
Source data
