General
Preferred name
TOCAINIDE
Synonyms
TOCAINIDE HYDROCHLORIDE ()
Tocainide (hydrochloride) ()
Tocainide monohydrochloride ()
Tonocard ()
Tocainide hcl ()
Xylotocan ()
W-36095 ()
Tocainide ()
P&D ID
PD002838
CAS
41708-72-9
35891-93-1
53984-26-2
76213-25-7
71395-14-7
Tags
natural product
drug
available
Approved by
FDA
First approval
1984
Drug Status
approved
withdrawn
Drug indication
Ventricular arrhythmias
Cardiac Depressant (anti-arrhythmic)
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Tocainide is a lidocaine analog.
(GtoPdb)
DESCRIPTION
Sodium channel blocker. Class IB antiarrhythmic.
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
19
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
LOPAC library
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
TargetMol Bioactive Compound Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
46
Molecular Weight
192.13
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
1.59
TPSA
55.12
Fraction CSP3
0.36
Chiral centers
1.0
Largest ring
6.0
QED
0.75
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Membrane Transporter/Ion Channel
Target
Sodium Channel
ATC
C01BB03
Therapeutic Class
Antiarrhythmic Agents
Source data
