General
Preferred name
ASPARTIC ACID
Synonyms
L-aspartic acid ()
Asparagic acid ()
Aspatofort ()
[3H]L-aspartic acid ()
FEMA NO. 3656 ()
Aspartate ()
Aspartic acid, l- ()
NSC-3973 ()
Deamidated asparagine ()
Aspartic acid,l ()
P&D ID
PD002813
CAS
56-84-8
27881-03-4
39162-75-9
181119-33-5
155436-59-2
Tags
natural product
drug
available
Approved by
FDA
Drug Status
nutraceutical
investigational
approved
Max Phase
Phase 3
Drug indication
Amino Acid
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION This ligand entry also represents L-aspartate (CHEBI:29993), the carboxylate anion and salt form of the acid. It is in the aspartate form that the ligand is transported across cell membranes. (GtoPdb)
DESCRIPTION Endogenous excitatory amino acid neurotransmitter (LOPAC library)
Compound Sets
18
ChEMBL Drugs
CHEMBL274323
Concise Guide to Pharmacology 2017/18
3309
4534
Concise Guide to Pharmacology 2019/20
3309
4534
Concise Guide to Pharmacology 2021/22
3309
4534
Concise Guide to Pharmacology 2023/24
3309
4534
Drug Repurposing Hub
DrugBank
DB00128
DrugBank Approved Drugs
DB00128
DrugCentral
1550
DrugCentral Approved Drugs
1550
DrugMAP
DMK7EYA
DMWGPO6
Guide to Pharmacology
3309
4534
LOPAC library
MedChem Express Bioactive Compound Library
HY-N0666
NPC Screening Collection
Selleckchem Bioactive Compound Library
l-aspartic-acid
TargetMol Bioactive Compound Library
T2O2731
The Spectrum Collection
External IDs
69
Properties
(calculated by RDKit )
Molecular Weight
133.04
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
3
Ring Count
0
Aromatic Ring Count
0
cLogP
-1.13
TPSA
100.62
Fraction CSP3
0.5
Chiral centers
1.0
Largest ring
0.0
QED
0.45
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
ACY1, ACY3, ADSS, ADSSL1, ASNS, ASPA, ASPH, ASRGL1, ASS1, CAD, DARS, DARS2, GOT1, GOT2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, LYZ, PAICS, RNASE1, SLC1A1, SLC25A12, SLC25A13
Endogenous Metabolite
MOA
metallic radical formation stimulant
Pathway
Metabolic Enzyme/Protease
Source data