General
Preferred name
ASPARTIC ACID
Synonyms
L-aspartic acid ()
Aspatofort ()
Asparagic acid ()
[3H]L-aspartic acid ()
Aspartic acid, l- ()
NSC-3973 ()
Acido aspartico ()
Deamidated asparagine ()
Acide aspartique ()
Aspartic acid,l ()
FEMA NO. 3656 ()
Aspartate ()
P&D ID
PD002813
CAS
27881-03-4
39162-75-9
181119-33-5
155436-59-2
56-84-8
Tags
available
drug
Approved by
FDA
Drug Status
approved
investigational
nutraceutical
Max Phase
3.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION Endogenous excitatory amino acid neurotransmitter (LOPAC library)
DESCRIPTION L-Aspartic acid is an amino acid commonly found as a component in total parenteral nutrition. It serves as a precursor for synthesis of proteins, oligopeptides, purines, pyrimidines, nucleic acids and L-arginine. It can also promote energy production via its metabolism in the Krebs cycle. (Enamine Bioactive Compounds)
DESCRIPTION L-Aspartic acid (Aspatofort) is a non-essential amino acid in humans, L-Aspartic acid has an overall negative charge and plays an important role in the synthesis of other amino acids and in the citric acid and urea cycles. Asparagine, arginine, lysine, methionine, isoleucine, and some nucleotides are synthesized from aspartic acid. L-Aspartic acid also serves as a neurotransmitter. (TargetMol Bioactive Compound Library)
Compound Sets
20
ChEMBL Drugs
CHEMBL274323
Concise Guide to Pharmacology 2017/18
3309
4534
Concise Guide to Pharmacology 2019/20
3309
4534
Concise Guide to Pharmacology 2021/22
3309
4534
Concise Guide to Pharmacology 2023/24
3309
4534
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DB00128
DrugBank Approved Drugs
DB00128
DrugCentral
1550
DrugCentral Approved Drugs
1550
DrugMAP
DMK7EYA
DMWGPO6
Enamine Bioactive Compounds
EBC-03203
Guide to Pharmacology
3309
4534
LOPAC library
MedChem Express Bioactive Compound Library
HY-N0666
NPC Screening Collection
Selleckchem Bioactive Compound Library
l-aspartic-acid
TargetMol Bioactive Compound Library
T2O2731
The Spectrum Collection
External IDs
72
Properties
(calculated by RDKit )
Molecular Weight
133.04
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
3
Ring Count
0
Aromatic Ring Count
0
cLogP
-1.13
TPSA
100.62
Fraction CSP3
0.5
Chiral centers
1.0
Largest ring
0.0
QED
0.45
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
ACY1, ACY3, ADSS, ADSSL1, ASNS, ASPA, ASPH, ASRGL1, ASS1, CAD, DARS, DARS2, GOT1, GOT2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, LYZ, PAICS, RNASE1, SLC1A1, SLC25A12, SLC25A13
MOA
metallic radical formation stimulant
Pathway
Metabolism
Metabolic Enzyme/Protease
Source data