General
Preferred name
ESATENOLOL
Synonyms
S(-)-Atenolol ()
S-(-)-Atenolol ()
(R)-(+)-Atenolol ()
(S)-Atenolol ()
(S)-(-)-Atenolol ()
Atenolol, (s)- ()
(-)-atenolol ()
S-Atenolol ()
(s)-atenolol ()
Atenolol, (-)- ()
P&D ID
PD002800
CAS
93379-54-5
56715-13-0
Tags
available
drug
Drug Status
approved
experimental
investigational
Max Phase
2.0
Drug indication
Cardiovascular disease
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION (S)-Atenolol is a potent beta-adrenoreceptor blocker. (S)-Atenolol has the potential for the research of cardiovascular disorder[1].
PRICE 160
DESCRIPTION beta1 adrenoceptor antagonist (LOPAC library)
DESCRIPTION β1-antagonist. Active isomer of atenolol (Cat. No. 0387) (Tocriscreen Total)
DESCRIPTION (S)-(-)-Atenolol is the active enantiomer of (RS)-atenolol, which is a cardioselective β-adrenergic blocker. It has antihypertensive, antianginal, antiarrhythmic (class II) effects. (BOC Sciences Bioactive Compounds)
DESCRIPTION (S)-(-)-Atenolol has beta-adrenergic blocking effects. (TargetMol Bioactive Compound Library)
Compound Sets
11
BOC Sciences Bioactive Compounds
s-atenolol-cas-93379-54-5-item-45365
ChEMBL Drugs
CHEMBL343633
Drug Repurposing Hub
DrugBank
DB13443
DrugCentral
4702
DrugCentral Approved Drugs
4702
LOPAC library
MedChem Express Bioactive Compound Library
HY-17498A
Prestwick Chemical Library
TargetMol Bioactive Compound Library
T35833
Tocriscreen Total
External IDs
27
Properties
(calculated by RDKit )
Molecular Weight
266.16
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
3
Rotatable Bonds
8
Ring Count
1
Aromatic Ring Count
1
cLogP
0.45
TPSA
84.58
Fraction CSP3
0.5
Chiral centers
1.0
Largest ring
6.0
QED
0.64
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
beta1
Target
β-adrenergic receptor
Adrenergic Receptor
Indication
hypertension
MOA
Adrenergic Receptor antagonist
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Source data