General
Preferred name
CYPROTERONE ACETATE
Synonyms
CYPROTERONE ()
Androcur ()
Cyproterone 17-O-acetate ()
cyproterone acetate, Barr ()
SH-714 ()
NSC-81430 ()
Diane ()
Cyprostat ()
Cyproterone ()
Androcur 10 ()
SH 714 ()
P&D ID
PD002761
CAS
427-51-0
Tags
natural product
drug
available
First approval
1974
Drug Status
investigational
approved
Max Phase
Phase 4
Drug indication
Anti-Androgen
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Cyproterone acetate is a steroidal, pure antiandrogen pharmaceutical agent. (GtoPdb)
DESCRIPTION Androgen antagonist; synthetic steroid (LOPAC library)
Cell lines
4
Organisms
3
Compound Sets
18
AdooQ Bioactive Compound Library
A11409
Cayman Chemical Bioactives
16622
ChEMBL Approved Drugs
CHEMBL139835
ChEMBL Drugs
CHEMBL139835
Drug Repurposing Hub
DrugBank
DB04839
DrugBank Approved Drugs
DB04839
DrugCentral
766
DrugCentral Approved Drugs
766
EU-OPENSCREEN Bioactive Compound Library
EOS101617
Guide to Pharmacology
2865
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL139835
NPC Screening Collection
NURSA ligand set
nursa/index.jsf?doi=10.1621%2F496ZOA3LLY
ReFrame library
Selleckchem Bioactive Compound Library
cyproterone-acetate
TargetMol Bioactive Compound Library
T1167
External IDs
37
Properties
(calculated by RDKit )
Molecular Weight
416.18
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
5
Aromatic Ring Count
0
cLogP
4.61
TPSA
60.44
Fraction CSP3
0.71
Chiral centers
8.0
Largest ring
6.0
QED
0.62
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Androgen
Pathway
Endocrinology/Hormones
Target
Androgen Receptor
ADORA1, AR
Indication
prostate cancer
MOA
Androgen Receptor antagonist
Source data