General
Preferred name
PIRENPERONE
Synonyms
R 47465 ()
R-47456, R-50656 ()
R-47,465 ()
R-47465 ()
NSC-760095 ()
Pirenperona ()
P&D ID
PD002686
CAS
75444-65-4
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Pirenperone (R 47465) is a 5-HT2 serotonin receptor antagonist. Pirenperone exhibits modest anxiolytic activity[1][2].
PRICE 97
DESCRIPTION 5-HT2 serotonin receptor antagonist (LOPAC library)
DESCRIPTION Pirenperone is a 5-HT2 serotonin receptor antagonist. (Enamine Bioactive Compounds)
DESCRIPTION Pirenperone is a putative 5-HT2 receptor antagonist with the central antiserotonergic and antidopaminergic action. (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
3
Compound Sets
16
ChEMBL Drugs
CHEMBL18331
Drug Repurposing Hub
DrugMAP
DM9T2G3
DrugMatrix
Enamine Bioactive Compounds
EBC-13354
Guide to Pharmacology
283
Ki Database
PIRENPERONE
LOPAC library
MedChem Express Bioactive Compound Library
HY-B1737
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
pirenperone
TargetMol Bioactive Compound Library
T2599
The Spectrum Collection
External IDs
27
Properties
(calculated by RDKit )
Molecular Weight
393.19
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
0
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
3
cLogP
3.28
TPSA
54.68
Fraction CSP3
0.35
Chiral centers
0.0
Largest ring
6.0
QED
0.62
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
5-HT2
Target
HTR2A, HTR7
5-HT Receptor
MOA
serotonin receptor antagonist
Pathway
GPCR/G protein
Neuronal Signaling
Neuroscience
Source data