General
Preferred name
PROPENTOFYLLINE
Synonyms
Hextol ()
propentofylline propionate ()
Hoe-285 ()
HWA-285 ()
HWA 285 ()
NSC-752424 ()
Propentophylline ()
P&D ID
PD002685
CAS
55242-55-2
Tags
natural product
drug
available
Drug indication
Alzheimer disease
Drug Status
investigational
approved
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Nerve growth factor stimulator; adenosine transport inhibitor; non-selective adenosine receptor antagonist
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
15
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
LOPAC library
Mcule NIBR MoA Box Subset
Natural product-based probes and drugs
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
27
Molecular Weight
306.17
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
0
Rotatable Bonds
7
Ring Count
2
Aromatic Ring Count
2
cLogP
1.07
TPSA
78.89
Fraction CSP3
0.6
Chiral centers
0.0
Largest ring
6.0
QED
0.72
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Transporter
Member status
member
MOA
Adenosine Reuptake Inhibitors
adenosine reuptake inhibitor, phosphodiesterase inhibitor
Indication
stroke
Target
PDE1A
Biosynthetic Origin
Nucleoside (Nucleobase)
Therapeutic Indication
Vasodilator
Cerebral
Therapeutic Class
Cardiovascular
Source data
