General
Preferred name
NEBOGLAMINE
Synonyms
CR 2249 ()
Cr2249 ()
Nebostinel ()
XY-2401 ()
P&D ID
PD002669
CAS
163000-63-3
Tags
available
drug candidate
Drug Status
investigational
Max Phase
Phase 2
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Facilitates glycine action at NMDA glutamate receptors
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
ChEMBL Drugs
LOPAC library
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
13
Molecular Weight
256.18
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
5
Ring Count
1
Aromatic Ring Count
0
cLogP
1.26
TPSA
92.42
Fraction CSP3
0.85
Chiral centers
1.0
Largest ring
6.0
QED
0.69
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
NMDA-Glycine
Member status
member
MOA
NMDA Glycine-Site Modulators
Norepinephrine Reuptake Inhibitors
Source data
