General
Preferred name
DEXFOSFOSERINE
Synonyms
DEXFOSFOSERINE HYDROCHLORIDE ()
O-Phospho-L-Serine ()
L-Serine O-phosphate ()
Phosphoserine ()
L-SOP ()
L-serine-O-phosphate ()
L-o-serine phosphate ()
NSC-90791 ()
O-phosphoryl-l-serine ()
Phosphoserine, dl- ()
GNF-Pf-1028 ()
Dexfosfoserina ()
Serine phosphate ()
Serophen ()
NSC-760136 ()
Energoserina ()
O-phosphoserine, l- ()
Dl-phosphoserine ()
Dl-o-phosphorylserine ()
Seriphos ()
L-phosphoserine ()
Fosforina ()
L-o-phosphoserine ()
P&D ID
PD002659
CAS
407-41-0
68762-59-4
Tags
available
drug
Drug indication
Discovery agent
Drug Status
investigational
approved
experimental
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Competitive NMDA glutamate receptor antagonist with close structural similarity to L-glutamate
(LOPAC library)
DESCRIPTION
O-Phospho-L-serine (Phosphoserine) is the phosphoric acid ester of serine.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
21
Cayman Chemical Bioactives
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
LOPAC library
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
62
Molecular Weight
185.01
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
4
Rotatable Bonds
4
Ring Count
0
Aromatic Ring Count
0
cLogP
-1.49
TPSA
130.08
Fraction CSP3
0.67
Chiral centers
1.0
Largest ring
0.0
QED
0.39
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
NMDA
Target
Amino Acids and Derivatives
Endogenous Metabolite
mGluR
NMDA Receptor
CFTR, GRM4, GRM6, GRM7, GRM8, KCNC4, PDPK1, PIM1, PRKACA, PRKCQ, PYGL, PYGM, REG1A, RHO, SERPINB3, SMAD2, TAOK2
GluR
MOA
membrane integrity inhibitor
Pathway
Metabolism
Neuroscience
GPCR/G protein
Metabolic Enzyme/Protease
Neuronal Signaling
Source data
