General
Preferred name
Phosphonoacetic acid
Synonyms
Fosfonet sodium ()
FOSFONET ()
PAA ()
NSC-18205 ()
NSC-138745 ()
ABBOTT-38642 ()
Fosfonet de sodio ()
Fosfonet sodique ()
Fosfonet sodium monohydrate ()
Fosfonet sodium anhydrous ()
P&D ID
PD002620
CAS
7230-09-3
4408-78-0
Tags
available
drug candidate
Drug Status
experimental
investigational
Max Phase
2.0
Drug indication
viral disease
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION DNA Polymerase inhibitor (LOPAC library)
DESCRIPTION Phosphonoacetate, also known as fosfonet or phosphonacetic acid, belongs to the class of organic compounds known as organic phosphonic acids.Within the cell, phosphonoacetate is primarily located in the cytoplasm. Phosphonoacetate can be biosynthesized from phosphonic acid and acetic acid. (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
1
Compound Sets
9
ChEMBL Drugs
CHEMBL50300
CHEMBL3989828
DrugBank
DB02823
DrugMatrix
LOPAC library
MedChem Express Bioactive Compound Library
HY-128744
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
phosphonoacetic-acid
TargetMol Bioactive Compound Library
T4729
External IDs
39
Properties
(calculated by RDKit )
Molecular Weight
139.99
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.75
TPSA
94.83
Fraction CSP3
0.5
Chiral centers
0.0
Largest ring
0.0
QED
0.44
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
DNA Polymerase
Target
Endogenous Metabolite
Human Endogenous Metabolite
DNA/RNA Synthesis
HSV
Orthopoxvirus
Antiviral,DNA/RNA Synthesis
Pathway
Metabolism
Anti-infection
Cell Cycle/DNA Damage
Metabolic Enzyme/Protease
Source data