General
Preferred name
TRIAMCINOLONE
Synonyms
Fluoxyprednisolone ()
Aristocort ()
Rodinolone ()
Cingal-triamcinolone ()
triamcinolone, Allergan ()
NSC-13397 ()
Volon ()
Fluoxiprednisolone ()
Kenacort ()
Aristocort A ()
Kenalog ()
Delphicort ()
P&D ID
PD002598
CAS
124-94-7
Tags
natural product
drug
available
Approved by
FDA
First approval
1957
Drug Status
withdrawn
approved
vet_approved
Drug indication
Allergic rhinitis
Glucocorticoid
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Triamcinolone is a synthetic glucocorticoid. The approved drug is often administered in the formulation .
DESCRIPTION
Triamcinolone is a synthetic glucocorticoid anti-inflammatory drug. The approved drug is often administered in the formulation . Hexacetonide, furetonide and benetonide forms are also used in the clinic, and have individual INNs.
(GtoPdb)
DESCRIPTION
Synthetic glucocorticoid agonist; inducer of gene expression and apoptosis
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
21
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
Natural product-based probes and drugs
NURSA ligand set
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
36
Molecular Weight
394.18
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
4
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
0
cLogP
0.62
TPSA
115.06
Fraction CSP3
0.71
Chiral centers
8.0
Largest ring
6.0
QED
0.55
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Glucocorticoid
Pathway
Immunology/Inflammation
Metabolism
Neuroscience
Vitamin D Related/Nuclear Receptor
Target
COX
Glucocorticoid Receptor
NR3C1
Interleukin Related
Indication
corticosteroid-responsive dermatoses
MOA
Glucocorticoid Receptor agonist
ATC
R03BA06
A01AC01
D07AB09
H02AB08
D07XB02
R01AD11
S01BA05
C05AA12
Biosynthetic Origin
Terpenoid (Steroid)
Therapeutic Indication
Antiarthritic
Therapeutic Class
Antiinflammatory
Antiinflammatory Agents
Source data
