General
Preferred name
IPRIFLAVONE
Synonyms
7-(1-Methyethoxy)-3-phenyl-4h-1-benzopyran-4-one ()
Osteofix ()
Osten ()
Ipriflavone (Osteofix) ()
NSC-755888 ()
Ipriflavona ()
Ostivone ()
7-isopropoxyisoflavone ()
P&D ID
PD002503
CAS
35212-22-7
Tags
available
drug
Drug indication
Osteoporosis
Bone disease
Drug Status
approved
experimental
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Ipriflavone is a synthetic isoflavone derivative used to suppress bone resorption.
PRICE 29
DESCRIPTION Ipriflavone (Osteofix) (Osteofix) is a feed additive and a catabolic agent. It is used to inhibit bone resorption. (TargetMol Bioactive Compound Library)
Cell lines
1
Organisms
2
Compound Sets
19
Cayman Chemical Bioactives
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
MedChem Express Bioactive Compound Library
Natural product-based probes and drugs
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
External IDs
33
Properties
(calculated by RDKit )
Molecular Weight
280.11
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
3
cLogP
4.25
TPSA
39.44
Fraction CSP3
0.17
Chiral centers
0.0
Largest ring
6.0
QED
0.72
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Indication
osteoporosis
MOA
bone resorption inhibitor
Biosynthetic Origin
Polyketide (Flavonoid)
Therapeutic Indication
Calcium Metabolism
Therapeutic Class
Hormone Therapy
Target
Cytochrome P450
advanced glycation end products
Pathway
Metabolic Enzyme/Protease
Source data