General
Preferred name
ANTIPYRINE
Synonyms
Phenazon ()
phenazone ()
DICHLORALPHENAZONE ()
Phenazone,Phenazon ()
NSC-7945 ()
Antipyrin ()
Antipyrinum ()
Dichloralantipyrine ()
Dichloralphenazone civ ()
P&D ID
PD002469
CAS
60-80-0
123175-91-7
480-30-8
Tags
natural product
drug
available
First approval
1964
Drug Status
illicit
investigational
approved
Drug indication
Analgesic
Discovery agent
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
INDICATION
Antipyrine is an analgesic often used to test effects of other drugs on liver enzymes.; ; In combination with benzocaine in otic solutions, antipyrine is indicated for the symptomatic relief of acute otitis media arising from various etiologies.
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
16
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMatrix
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
47
Molecular Weight
188.09
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
1
Ring Count
2
Aromatic Ring Count
2
cLogP
1.48
TPSA
26.93
Fraction CSP3
0.18
Chiral centers
0.0
Largest ring
6.0
QED
0.67
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Immunology/Inflammation
Neuroscience
Target
COX
PTGS1, PTGS2
Indication
pain relief
MOA
cyclooxygenase inhibitor
Source data
