General
Preferred name
CEFAZOLIN SODIUM
Synonyms
Sodium cephazolin ()
Sodium cefazolin ()
cefazoline sodium ()
cephazolin sodium ()
Ancef ()
Cefazolin sodium salt ()
Cefazolin (sodium) ()
Cephazolin (sodium) ()
cefazoline sodium, cephazolin sodium, Ancef ()
46083 ()
Gramaxin ()
Cefamedin ()
SK&F 41558 ()
Zolicef ()
Cefamezin ()
Totacef ()
NSC-291561 ()
Cefazolin and dextrose ()
Cefazolin injection ()
Cefazil ()
Cephazolin ()
Cefacidal ()
Kefzol ()
Cefazolin (sodium salt) ()
P&D ID
PD002440
CAS
27164-46-1
25953-19-9
Tags
natural product
drug
available
Drug Status
approved
Max Phase
Phase 4
Drug indication
Antibacterial (systemic)
First approval
1973
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Semi-synthetic antibiotic; interferes with cell wall synthesis (LOPAC library)
Cell lines
0
Organisms
1
Compound Sets
11
Cayman Chemical Bioactives
15776
ChEMBL Approved Drugs
CHEMBL1200523
ChEMBL Drugs
CHEMBL1200523
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
EOS100569
LOPAC library
MedChem Express Bioactive Compound Library
HY-B1078
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
cefazolin-sodium
TargetMol Bioactive Compound Library
T0953
The Spectrum Collection
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
476.01
Hydrogen Bond Acceptors
13
Hydrogen Bond Donors
1
Rotatable Bonds
7
Ring Count
4
Aromatic Ring Count
2
cLogP
-4.97
TPSA
158.92
Fraction CSP3
0.43
Chiral centers
2.0
Largest ring
6.0
QED
0.23
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Cell wall synthesis
Pathway
Microbiology&virology
Anti-infection
Target
PBPs
Peptidoglycan synthase
PON
antibiotic
Bacterial
Antibiotics,Bacterial
Source data