General
Preferred name
CHLORPROMAZINE HYDROCHLORIDE
Synonyms
Chlorpromazine HCl ()
Sonazine ()
Chlorpromazine (HCl) ()
Chloractil ()
Largactil ()
NSC-17479 ()
Rimazine ()
Norcozine ()
Chlorazine ()
Promapar ()
Chlorpromazini hydrochloridum ()
Nci-c05210 ()
Chlorpromazine Hydrochloride Intensol ()
Largactil Fte ()
Klorproman ()
Marazine ()
Thorazine ()
Chlorpromazine (hydrochloride) ()
P&D ID
PD002424
CAS
69-09-0
Tags
nuisance
natural product
drug
available
Drug Status
approved
Max Phase
Phase 4
Drug indication
Anti-Emetic
Antipsychotic
First approval
1957
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Dopamine receptor antagonist; anti-emetic; antipsychotic
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
2
Compound Sets
13
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Enamine BioReference Compounds
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
NIH Clinical Collections (NCC)
Nuisance compounds in cellular assays
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Molecular Weight
354.07
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
2
cLogP
5.32
TPSA
6.48
Fraction CSP3
0.29
Chiral centers
0.0
Largest ring
6.0
QED
0.73
Structural alerts
4
aggregator (Aggregator Advisor)
Aggregators
historic compounds (Chemical Probes.org)
Obsolete
aggregator (ZINC)
Aggregators
CAD
Nuisance compounds in cellular assays
Custom attributes
(extracted from source data)
Target
Potassium Channel
5-HT2A
D2
Dopamine Receptor,Potassium Channel
Pathway
GPCR/G protein
Neuroscience
Source data