General
Preferred name
CHLORPROMAZINE HYDROCHLORIDE
Synonyms
Chlorpromazine HCl ()
Sonazine ()
Chlorpromazine (HCl) ()
Chloractil ()
Chlorpromazine Hydrochloride Intensol ()
Largactil Fte ()
Promapar ()
Klorproman ()
Rimazine ()
Norcozine ()
Nci-c05210 ()
Chlorazine ()
Chlorpromazini hydrochloridum ()
NSC-17479 ()
Thorazine ()
Largactil ()
Marazine ()
Chlorpromazine (hydrochloride) ()
P&D ID
PD002424
CAS
69-09-0
Tags
available
nuisance
drug
Drug Status
approved
Max Phase
4.0
Drug indication
Antipsychotic
Anti-Emetic
First approval
1957
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Dopamine receptor antagonist; anti-emetic; antipsychotic (LOPAC library)
Cell lines
0
Organisms
2
Compound Sets
13
AdooQ Bioactive Compound Library
A10206
Cayman Chemical Bioactives
16129
ChEMBL Approved Drugs
CHEMBL1713
ChEMBL Drugs
CHEMBL1713
Enamine BioReference Compounds
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL1713
NIH Clinical Collections (NCC)
Nuisance compounds in cellular assays
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
Chlorpromazine-hydrochloride(Sonazine)
TargetMol Bioactive Compound Library
T1384
The Spectrum Collection
External IDs
26
Properties
(calculated by RDKit )
Molecular Weight
354.07
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
2
cLogP
5.32
TPSA
6.48
Fraction CSP3
0.29
Chiral centers
0.0
Largest ring
6.0
QED
0.73
Structural alerts
4
aggregator (ZINC)
Aggregators
aggregator (Aggregator Advisor)
Aggregators
historic compounds (Chemical Probes.org)
Obsolete
CAD
Nuisance compounds
Related compounds
Custom attributes
(extracted from source data)
Target
Potassium Channel
5-HT2A
D2
Dopamine Receptor,Potassium Channel
Pathway
GPCR/G protein
Neuroscience
Source data