General
Preferred name
CLOFIBRIC ACID
Synonyms
Calcium clofibrate ()
Chlorofibrinic acid ()
Fibrates ()
moroxybrate ()
2-(p-Chlorophenoxy)-2-methylpropionic acid ()
MAGNESIUM CLOFIBRATE ()
ALUMINUM CLOFIBRATE ()
Aluminium clofibrate ()
Acide clofibrique ()
NSC-1149 ()
Acido clofibrico ()
Clofibrato de aluminio ()
Clofibrate d'aluminium ()
Clofibric acid basic aluminum salt ()
Clofibrate de magnesium ()
Clofibrate magnesico chobet ()
Clofibric acid magnesium salt ()
Clofibrato de magnesio ()
Clofibrato de calcio ()
Clofibrate de calcium ()
Clofibric Acid-d4 ()
P&D ID
PD002414
CAS
882-09-7
24818-79-9
39087-48-4
14613-30-0
1184991-14-7
Tags
available
drug
drug candidate
First approval
1963
Drug indication
Dyslipidemia
Cardiovascular disease
Drug Status
approved
experimental
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Clofibric acid (Chlorofibrinic acid) is an orally active PPAR¦Á agonist. Clofibric acid inhibits the fimbriation of Escherichia coli. Clofibric acid increases SOD activity. Clofibric acid lowers blood lipids and prevents experimental pyelonephritis. Clofibric acid has anticancer activity against ovarian cancer. Clofibric acid is also a herbicide. Clofibric acid is used in ovarian cancer, liver cancer, obesity, and urinary tract infection research[1][2][3][4][5][6][7][8][9].
PRICE
29
DESCRIPTION
PPAR agonist
(Tocriscreen Total)
DESCRIPTION
Clofibric acid is a PPAR agonist.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Clofibric acid is a fibric acid derivative used to lower cholesterol and triglyceride (fat-like substances) levels in the blood. It is an agonist of the PPAR-α receptor in muscle, liver, and other tissues.
(Enamine Bioactive Compounds)
DESCRIPTION
Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
19
BOC Sciences Bioactive Compounds
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMatrix
Enamine Bioactive Compounds
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
66
Molecular Weight
214.04
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
2.58
TPSA
46.53
Fraction CSP3
0.3
Chiral centers
0.0
Largest ring
6.0
QED
0.84
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Drug Metabolite
PPAR
Apoptosis
PPARA
Bacterial
SOD
Indication
hyperlipidemia
MOA
PPAR receptor agonist
Pathway
DNA Damage/DNA Repair
Metabolism
Anti-infection
Cell Cycle/DNA Damage
Immunology/Inflammation
Metabolic Enzyme/Protease
Vitamin D Related/Nuclear Receptor
Source data
