General
Preferred name
DIBUCAINE HYDROCHLORIDE
Synonyms
Dibucaine (hydrochloride) ()
Cinchocaine hydrochloride ()
Dibucaine HCl ()
Cinchocaine HCl ()
Nupercaine ()
Cincaine Chloride ()
NSC-756724 ()
Heavy Solution Nupercaine ()
Nupercainal ()
P&D ID
PD002383
CAS
61-12-1
85-79-0
Tags
natural product
drug
available
Drug Status
approved
Max Phase
Phase 4
Drug indication
Anesthetic (local)
First approval
1982
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Dibucaine HCl is a local anesthetics.Among the most potent and toxic of the long-acting local anesthetics, current use of it is generally restricted to spinal and topical anesthesia.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
BOC Sciences Bioactive Compounds
ChEMBL Approved Drugs
ChEMBL Drugs
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
19
Molecular Weight
379.2
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
10
Ring Count
2
Aromatic Ring Count
2
cLogP
3.91
TPSA
54.46
Fraction CSP3
0.5
Chiral centers
0.0
Largest ring
6.0
QED
0.64
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Membrane Transporter/Ion Channel
Target
Sodium Channel
Source data
