General
Preferred name
DIMERCAPROL
Synonyms
Dicaptol ()
Dithiopropanol ()
2,3-Dimercapto-1-propanol ()
Dithioglycerol ()
Bal, 2,3-Dimercapto-1-propanol, Dithioglycerol ()
Dimersol ()
1-propanol, 2,3-dimercapto ()
2,3-dithiopropanol ()
2,3-dithiopropan-1-ol ()
Panobal ()
Anti-Lewisite ()
Sulfactin ()
NSC-39515 ()
B.A.L. ()
BAL ()
Antoxol ()
Dimercaprolum ()
NSC-4646 ()
2,3,-dimercapto-1-propanol ()
P&D ID
PD002368
CAS
59-52-9
31855-41-1
Tags
available
drug
Approved by
FDA
First approval
1946
Drug Status
approved
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PHARMACODYNAMICS
Due to its oily nature, dimercaprol is not absorbed orally and its administration requires a deep intra-muscular injection that is extremely painful and allergenic. It was found to mobilize and relocate lead to the brain, increasing its neurotoxic effects. Despite that fact that dimercaprol increases cadmium excretion, there is an associated increase in kidney cadmium concentration. Because of this, dimercaprol must be avoided in patients with cadmium toxicity.
PRICE
29
DESCRIPTION
Dimercaprol is a chelating agent used as an antidote to arsenic, gold, and mercury poisoning, as well as acute lead poisoning in combination with edetate calcium disodium.
(Enamine Bioactive Compounds)
DESCRIPTION
Dimercaprol (Dicaptol) is an anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisonings.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
13
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
Enamine Bioactive Compounds
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
44
Molecular Weight
124.0
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
0
Aromatic Ring Count
0
cLogP
0.21
TPSA
20.23
Fraction CSP3
1.0
Chiral centers
1.0
Largest ring
0.0
QED
0.45
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
HIV
Mercury
Pathway
Microbiology/virology
Proteases/Proteasome
Anti-infection
Source data
