General
Preferred name
DOXYLAMINE SUCCINATE
Synonyms
Decapryn ()
NSC-74772 ()
Donormyl ()
Dormidina ()
Gittalun ()
Unisom ()
Alsodorm ()
Doxy-Sleep-Aid ()
Hoggar n ()
Doxylamine hydrogen succinate ()
Meraprina ()
Donormil ()
Doxylamine (succinate) ()
P&D ID
PD002356
CAS
562-10-7
469-21-6
Tags
natural product
drug
available
Drug Status
approved
Max Phase
Phase 4
Drug indication
Antihistaminic
First approval
1948
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
H1 Histamine receptor antagonist
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
9
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
LOPAC library
NIH Clinical Collections (NCC)
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
19
Molecular Weight
388.2
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
9
Ring Count
2
Aromatic Ring Count
2
cLogP
2.86
TPSA
99.96
Fraction CSP3
0.38
Chiral centers
1.0
Largest ring
6.0
QED
0.68
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
H1
Pathway
GPCR/G protein
Immunology/Inflammation
Neuroscience
Target
H1 receptor
Histamine Receptor
Source data
