General
Preferred name
EUGENOL
Synonyms
2-Methoxy-4-(2-propenyl)phenol ()
4-Allylguaiacol ()
Allylguaiacol ()
4-Allyl-2-methoxyphenol ()
Eugenic acid ()
Eugenol,98% (stabilized with TBC) ()
4-Allyl-2-methoxyphenol, 4-Allylguaiacol, Eugenic acid, Allylguaiacol ()
NSC-8895 ()
4-allylcatechol 2-methyl ether ()
FEMA NO. 2467 ()
NSC-209525 ()
Caryophillic acid ()
Dentogum ()
Bioxeda ()
Eugenol ()
P&D ID
PD002332
CAS
97-53-0
Tags
available
drug
natural product
nuisance
Approved by
FDA
Drug indication
Discovery agent
Drug Status
approved
investigational
Max Phase
0.5
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Eugenol is a phenolic compound that is primarily found in oil extracted from cloves.
(GtoPdb)
DESCRIPTION
Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation.
PRICE
29
DESCRIPTION
Eugenol is a phenol used for the temporary relief of toothaches. It has been found to have anti-inflammatory, neuroprotective, antipyretic, antioxidant, antifungal and analgesic properties. It inhibits Phosphoethanolamine transferase Mcr-1 (Escherichia coli), Acetylcholinesterase (Psoroptes cuniculi).
(Enamine Bioactive Compounds)
DESCRIPTION
Eugenol (Allylguaiacol) is a Standardized Chemical Allergen. The physiologic effect of eugenol is by means of Increased Histamine Release and Cell-mediated Immunity.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
1
Compound Sets
24
AdooQ Bioactive Compound Library
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMatrix
Enamine Bioactive Compounds
Enamine BioReference Compounds
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NPC Screening Collection
Nuisance compounds in cellular assays
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
41
Molecular Weight
164.08
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
2.13
TPSA
29.46
Fraction CSP3
0.2
Chiral centers
0.0
Largest ring
6.0
QED
0.69
Structural alerts
1
Nonspecific/NOS
IMP
Nuisance compounds
Related compounds
Custom attributes
(extracted from source data)
Pathway
NF-¦ÊB
Immunology/Inflammation
Metabolism
Microbiology/virology
NF-κB
Anti-infection
Metabolic Enzyme/Protease
Target
Antibacterial
Apoptosis
Bacterial
Ferroptosis
Parasite
Reactive Oxygen Species
AR
Reactive Oxygen Species (ROS)
Immunology & Inflammation related
Indication
toothache
MOA
Androgen Receptor antagonist
Source data
