General
Preferred name
GALLAMINE TRIETHIODIDE
Synonyms
Flaxedil ()
Benzkurin ()
Gallomone Triethiodide ()
NSC-102690 ()
Gallamone Triethiodide ()
Benzcurine Iodide ()
Gallamini triethiodidum ()
Syncurarine ()
Remyolan ()
Relaxan ()
Gallamine (iodide) ()
P&D ID
PD002322
CAS
65-29-2
153-76-4
Tags
available
drug
Drug Status
approved
Drug indication
Stabilize muscle contraction
Neuromuscular Blocking Agent
Max Phase
Phase 4
First approval
1982
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
M2 muscarinic acetylcholine receptor antagonist; muscle relaxant
(LOPAC library)
DESCRIPTION
Gallamine Triethiodide is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM. It is is a non-depolarising muscle relaxant.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
19
AdooQ Bioactive Compound Library
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
19
Molecular Weight
891.18
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
21
Ring Count
1
Aromatic Ring Count
1
cLogP
-3.54
TPSA
27.69
Fraction CSP3
0.8
Chiral centers
0.0
Largest ring
6.0
QED
0.09
Structural alerts
2
aggregator (Aggregator Advisor)
Aggregators
aggregator (ZINC)
Aggregators
Related compounds
Custom attributes
(extracted from source data)
Selectivity
M2
Pathway
Neuroscience
GPCR/G protein
Neuronal Signaling
Target
AChR
mAChR
MOA
AChR antagonist
Therapeutic Class
Skeletal Muscle Relaxants
Source data
