General
Preferred name
INDAPAMIDE
Synonyms
Veroxil ()
Noranat ()
Tertensif ()
Indapamide (Lozol) ()
Indapamide ()
Indaflex ()
Natrix ()
Indapamide component of br-1015 ()
Fludex ()
NSC-757075 ()
Lozol ()
SE-1520 ()
S-1520 ()
Varbim XL ()
Ethibide XL ()
Tandix ()
Nindaxa 2.5 ()
Arifon ()
Flupamid ()
Indipam XL ()
Indamol ()
Mapemid XL ()
Fludin ()
Natrilix ()
Natrilix SR ()
Indapamida ()
Opumide 2.5 ()
Tensaid XL ()
KYD-041 ()
Lorvas ()
Bajaten ()
Rawel XL ()
Ipamix ()
Indamide ()
Indaxa 2.5 ()
Cardide SR ()
Flubest ()
Damide ()
Indapamide-13C-d3 ()
P&D ID
PD002293
CAS
26807-65-8
2934053-07-1
Tags
available
drug
Approved by
FDA
First approval
1983
Drug indication
Hypertension
Drug Status
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Indapamide is a thiazide diuretic drug. (GtoPdb)
DESCRIPTION Indapamide is an orally active sulphonamide diuretic agent, that can reduce blood pressure by decreasing vascular reactivity and peripheral vascular resistance. Indapamide is also can reduce left ventricular hypertrophy[1][4].
DESCRIPTION Indapamide is a non-thiazide sulphonamide diuretic compound that blocks delayed-rectifier potassium currents, generally used in the treatment of hypertension, as well as decompensated cardiac failure. Carbonic anhydrase inhibitor (Enamine Bioactive Compounds)
DESCRIPTION Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure. (TargetMol Bioactive Compound Library)
Compound Sets
26
AdooQ Bioactive Compound Library
A10470
Cayman Chemical Bioactives
21308
34244
ChEMBL Approved Drugs
CHEMBL406
ChEMBL Drugs
CHEMBL406
DrugBank
DB00808
DrugBank Approved Drugs
DB00808
DrugCentral
1433
DrugCentral Approved Drugs
1433
DrugMAP
DMGN1PW
DrugMAP Approved Drugs
DMGN1PW
DrugMatrix
Enamine Bioactive Compounds
EBC-06876
Enamine BioReference Compounds
Guide to Pharmacology
7203
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL406
Mcule NIBR MoA Box Subset
MCULE-1549472772
MedChem Express Bioactive Compound Library
HY-B0259
NCATS Inxight Approved Drugs
F089I0511L
NIH Clinical Collections (NCC)
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
Indapamide(Lozol)
TargetMol Bioactive Compound Library
T1498
The Spectrum Collection
External IDs
43
Properties
(calculated by RDKit )
Molecular Weight
365.06
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
2
cLogP
2.08
TPSA
92.5
Fraction CSP3
0.19
Chiral centers
1.0
Largest ring
6.0
QED
0.87
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Potassium Channel
Member status
member
MOA
Carbonic Anhydrase Type VII Inhibitors
Therapeutic Class
Antihypertensive Agents
Pathway
Membrane Transporter/Ion Channel
Source data