General
Preferred name
GRISEOFULVIN
Synonyms
Amudane ()
Fulvicin ()
Grisactin ()
Griseofulvin126-07-8 ()
Grisactin v ()
Griseofulvin microsize ()
Fulcin 125 ()
Fulsovin ()
Gris-Peg ()
Grisol AF ()
Griseofulvin permeability diameter ()
Griseofulvin, Ultramicrosize ()
NSC-34533 ()
Grisactin Ultra ()
Fulvicin P/G ()
Griseofulvin, microcrystalline ()
Griseofulvin,Ultramicrosize ()
Fulvicin-U/F ()
Grivate ()
Griseofulvin, ultramicrocrystalline ()
Griseofulvinum ()
Fulvicin P/G 330 ()
NSC-755822 ()
Fulcin 500 ()
Griseofulvin, Microsize ()
Grifulvin ()
Ultragris-165 ()
Fulcin ()
Grifulvin V ()
Fulvicin P/G 165 ()
Griseofulvin,microsize ()
Ultragris-330 ()
Fulvicin-P/G ()
Griseofulvin-d3 ()
P&D ID
PD002235
CAS
126-07-8
107912-37-8
1279033-22-5
Tags
natural product
drug
available
Approved by
FDA
First approval
1962
Drug Status
investigational
approved
vet_approved
Drug indication
Ringworm infection
Antifungal
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
10
Organisms
7
Compound Sets
23
AdooQ Bioactive Compound Library
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Enamine BioReference Compounds
Mcule NIBR MoA Box Subset
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NIH Clinical Collections (NCC)
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
50
Properties
(calculated by RDKit )
Molecular Weight
352.07
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
0
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
1
cLogP
2.81
TPSA
71.06
Fraction CSP3
0.41
Chiral centers
2.0
Largest ring
6.0
QED
0.83
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Cytoskeletal Signaling
Anti-infection
Apoptosis
Metabolic Enzyme/Protease
Target
Tubulin chain
KRT12
antibiotic
Endogenous Metabolite
Fungal
Microtubule Associated
Member status
member
MOA
Keratin 12 modulator
tubulin polymerization inhibitor
Indication
ringworm, tinea pedis
Therapeutic Class
Antifungal Agents
Source data
