General
Preferred name
TYRAMINE
Synonyms
4-Hydroxyphenethylamine hydrochloride ()
p-Tyramine ()
Uteramine ()
4-hydroxyphenethylamine ()
para-tyramine ()
Tocosine ()
Triton WR1339 ()
Tyramine (hydrochloride) ()
4-hydroxyphenethylamine, para-tyramine, mydrial, uteramin ()
TYRAMINE HYDROCHLORIDE ()
2-p-hydroxyphenylethylamine ()
Tyrosamine ()
FEMA NO. 4215 ()
Systogene ()
NSC-249188 ()
Ractopamine hydrochloride suspension impurity, tyramine- ()
Tyramine-d4 (hydrochloride) ()
P&D ID
PD002144
CAS
51-67-2
60-19-5
1189884-47-6
Tags
available
drug
Drug indication
Discovery agent
Orthostatic hypotension
Drug Status
approved
investigational
nutraceutical
Max Phase
3.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Tyramine is an amino acid that helps regulate blood pressure. Tyramine occurs naturally in the body, and it's found in certain foods[1].
PRICE 29
DESCRIPTION Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods[1].
PRICE 29
DESCRIPTION Tyramine (Uteramine) is an indirect sympathomimetic that occurs naturally in cheese and other foods. Tyramine does not directly activate adrenergic receptors, but it can serve as a substrate for adrenergic uptake systems and MONOAMINE OXIDASE to prolong the actions of adrenergic transmitters. It also provokes transmitter release from adrenergic terminals and may be a neurotransmitter in some invertebrate nervous systems. (TargetMol Bioactive Compound Library)
DESCRIPTION Dopamine receptor agonist (LOPAC library)
DESCRIPTION Tyramine is an amino acid that helps regulate blood pressure. Tyramine is a trace amine-associated receptor 1 (TAAR1), 5-hydroxytryptamine and octopamine agonist. (Enamine Bioactive Compounds)
DESCRIPTION Tyramine hydrochloride is a biogenic trace amine that is generated via the decarboxylation of the amino acid tyrosine, exhibiting neuromodulatory properties as well as cardiovascular and immunological effects. (TargetMol Bioactive Compound Library)
Compound Sets
22
Cayman Chemical Bioactives
18601
28531
ChEMBL Drugs
CHEMBL11608
Concise Guide to Pharmacology 2017/18
2148
2150
Concise Guide to Pharmacology 2019/20
2148
2150
Concise Guide to Pharmacology 2021/22
2148
2150
Concise Guide to Pharmacology 2023/24
2148
2150
CZ-OPENSCREEN Bioactive Library
DrugBank
DB08841
DrugCentral
2784
DrugCentral Approved Drugs
2784
DrugMAP
DM4UXT1
Enamine Bioactive Compounds
EBC-253047
EU-OPENSCREEN Bioactive Compound Library
EOS100944
Guide to Pharmacology
2148
2150
Ki Database
Tyramine
LOPAC library
MedChem Express Bioactive Compound Library
HY-W007606
HY-W016823
ReFrame library
Selleckchem Bioactive Compound Library
tyramine
tyramine-hydrochloride
TargetMol Bioactive Compound Library
T3095
T7851
The Spectrum Collection
ZINC Tool Compounds
ZINC000000002233
External IDs
65
Properties
(calculated by RDKit )
Molecular Weight
137.08
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
0.89
TPSA
46.25
Fraction CSP3
0.25
Chiral centers
0.0
Largest ring
6.0
QED
0.64
QED
0.64
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
MAOs
TAAR
Pathway
Metabolism
Neuroscience
Metabolic Enzyme/Protease
Source data