General
Preferred name
GENTISIC ACID
Synonyms
5-Hydroxysalicylic acid ()
Phloretate ()
Carboxyhydroquinone ()
Hydroquinonecarboxylic acid ()
Gentianic acid ()
2,5-dihydroxybenzoic acid ()
DHB, 2,5-dihydroxybenzoic acid, 5-Hydroxysalicylic acid, Gentianic acid, Carboxyhydroquinone, Hydroquinonecarboxylic acid ()
P&D ID
PD002127
CAS
490-79-9
Tags
available
drug
Drug Status
approved
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 2,5-Dihydroxybenzoic acid is a derivative of benzoic and a powerful inhibitor of fibroblast growth factors.
PRICE 29
DESCRIPTION Gentisic acid is a benzoic acid that has been found in Gentiana and an active metabolite of aspirin with diverse biological activities. It has anti-inflammatory, antirheumatic and antioxidant properties. (Enamine Bioactive Compounds)
DESCRIPTION 2,5-Dihydroxybenzoic acid (Gentisic acid) is an active metabolite of salicylic acid degradation with a broad spectrum of biological activity, such as anti-inflammatory, antirheumatic and antioxidant properties. (TargetMol Bioactive Compound Library)
Compound Sets
9
DrugCentral
3260
DrugCentral Approved Drugs
3260
Enamine Bioactive Compounds
EBC-48155
MedChem Express Bioactive Compound Library
HY-W001179
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
gentisic-acid
TargetMol Bioactive Compound Library
T2857
The Spectrum Collection
External IDs
34
Properties
(calculated by RDKit )
Molecular Weight
154.03
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
1
cLogP
0.8
TPSA
77.76
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.52
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
FGFR
Immunology & Inflammation related
Pathway
Angiogenesis
Metabolism
Tyrosine Kinase/Adaptors
Metabolic Enzyme/Protease
Protein Tyrosine Kinase/RTK
Source data