General
Preferred name
Trifluoperazine dihydrochloride
Synonyms
TRIFLUOPERAZINE HYDROCHLORIDE ()
TFP ()
SKF5019 ()
Urinox ()
Trifluoperazine 2HCl ()
Trifluoperazine (HCl) ()
Stelazine ()
NSC-757369 ()
Trifluoperazine HCl ()
Trifluoperazine Dihydrochloride ()
Trifluoperazine Maleate ()
Trifluoperazine (hydrochloride) ()
P&D ID
PD002105
CAS
440-17-5
Tags
nuisance
natural product
drug
available
Drug Status
approved
Max Phase
Phase 4
First approval
1959
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Calmodulin antagonist; dopamine receptor antagonist; antipsychotic; sedative
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
1
Compound Sets
10
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Enamine BioReference Compounds
LOPAC library
Nuisance compounds in cellular assays
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
22
Molecular Weight
479.12
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
4
Aromatic Ring Count
2
cLogP
5.79
TPSA
9.72
Fraction CSP3
0.43
Chiral centers
0.0
Largest ring
6.0
QED
0.55
Structural alerts
2
historic compounds (Chemical Probes.org)
Obsolete
CAD
Nuisance compounds in cellular assays
Related compounds
Custom attributes
(extracted from source data)
Selectivity
D1/D2
Target
Autophagy
D2
Influenza Virus
Adrenergic Receptor
Dopamine Receptor
Pathway
GPCR/G protein
Neuroscience
Anti-infection
Source data
