General
Preferred name
CINNAMIC ACID
Synonyms
¦Â-Phenylacrylic acid ()
Cinnamylic acid ()
trans-3-Phenylacrylic acid ()
Isocinnamic acid ()
Phenylacrylic acid ()
3-Phenylacrylic acid ()
trans-Cinnamic acid, Phenylacrylic acid, Cinnamylic acid, 3-Phenylacrylic acid|(E)-Cinnamic acid ()
??Phenylacrylic acid ()
Myricitrine ()
trans-Cinnamic acid ()
β-Phenylacrylic acid ()
trans-Cinnamic acid, Phenylacrylic acid, Cinnamylic acid, 3-Phenylacrylic acid ()
(E)-Cinnamic acid, Benzenepropenoic acid, Isocinnamic acid ()
P&D ID
PD002063
CAS
621-82-9
140-10-3
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
investigational
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 ¦Ìg/mL against fish pathogen A. sobria, SY-AS1[1].
DESCRIPTION
Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells.
PRICE
29
DESCRIPTION
Cinnamic acid is a natural antimicrobial. It also inhibits carbonic anhydrases.
(Enamine Bioactive Compounds)
DESCRIPTION
trans-Cinnamic acid (Myricitrine) exerts anti-diabetic activity by improving glucose tolerance in vivo and by stimulating insulin secretion in vitro.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
4
Organisms
3
Compound Sets
8
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
47
Molecular Weight
148.05
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
1.78
TPSA
37.3
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.65
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Antibacterial
Bacterial
Endogenous Metabolite
Pathway
Microbiology&virology
Metabolism
Microbiology/virology
Anti-infection
Metabolic Enzyme/Protease
Source data
