General
Preferred name
HESPERETIN
Synonyms
NSC-57654 ()
P&D ID
PD001966
CAS
520-33-2
41001-90-5
Tags
natural product
drug
available
Drug indication
High blood cholesterol level
Drug Status
experimental
approved
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Hesperetin is a natural flavonoid. It has antibacterial activity against Gram-negative H. pylori .
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
3
Organisms
0
Compound Sets
14
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
43
Molecular Weight
302.08
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
2
cLogP
2.52
TPSA
96.22
Fraction CSP3
0.19
Chiral centers
1.0
Largest ring
6.0
QED
0.79
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Stem Cells
Neuroscience
Apoptosis
Autophagy
MAPK/ERK Pathway
Target
HT
TGF??
DGAT1, MTTP, SOAT1, SOAT2
p38 MAPK
Histamine Receptor,TGF-beta/Smad
Member status
member
MOA
Lipid Lowering Agents
Antioxidants
Triglyceride Lowering Agents
Cytochrome P450 CYP1B1 Inhibitors
TRPM3 Antagonists
ACAT inhibitor
Therapeutic Class
Anticholesteremic Agents
Source data
