General
Preferred name
SANGUINARIUM CHLORIDE
Synonyms
Sanguinarine chloride ()
Pseudochelerythrine chloride ()
Sanguinarin (chloride) ()
Sanguinarium (chloride) ()
Pseudochelerythrine (chloride) ()
Sanguinarine (chloride) ()
Viadent ()
Sanguinarine Chloride ()
P&D ID
PD001955
CAS
5578-73-4
Tags
available
drug candidate
natural product
Drug Status
investigational
Max Phase
2.0
Drug indication
Antimicrobial
Anti-Inflammatory
Antifungal
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Inhibitor of Mg2+ and Na+/K+-ATPase; isolated from the leaves and stems of Macleaya cordata and microcarpa (LOPAC library)
DESCRIPTION HMG-CoA reductase inhibitor (Tocris Bioactive Compound Library)
Cell lines
3
Organisms
1
Compound Sets
9
Cayman Chemical Bioactives
16951
ChEMBL Drugs
CHEMBL490129
DrugMatrix
LOPAC library
MedChem Express Bioactive Compound Library
HY-N0052A
Selleckchem Bioactive Compound Library
sanguinarine-chloride
TargetMol Bioactive Compound Library
T0129
The Spectrum Collection
Tocris Bioactive Compound Library
2302
External IDs
14
Properties
(calculated by RDKit )
Molecular Weight
367.06
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
0
Ring Count
6
Aromatic Ring Count
4
cLogP
0.43
TPSA
40.8
Fraction CSP3
0.15
Chiral centers
0.0
Largest ring
6.0
QED
0.33
QED
0.33
Structural alerts
2
aggregator (Aggregator Advisor)
Aggregators
aggregator (ZINC)
Aggregators
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Na+/K+ ATPase
Pathway
Angiogenesis
JAK/STAT Signaling
Tyrosine Kinase/Adaptors
Anti-infection
Apoptosis
Autophagy
Target
Egr-1
VEGFR
Bacterial
Parasite
phosphatase,ROS
Primary Target
Protein Ser/Thr Phosphatases
MOA
Inhibitor
Source data