General
Preferred name
DIMPYLATE
Synonyms
Diazinon ()
Optimizer insecticide ()
G-24480 ()
New z diazinon ()
NSC-8938 ()
Dimpilato ()
Diazinon-d10 ()
P&D ID
PD001939
CAS
333-41-5
27936-40-9
100155-47-3
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Diazinon is an orally active, irreversible AChE inhibitor and insecticide that can be absorbed through the digestive system, skin or respiratory tract. Diazinon inhibits AChE, leading to accumulation of acetylcholine, which in turn overstimulates ACh receptors and affects the nervous system. Diazinon also produces reactive oxygen species (ROS)£¬ which induce oxidative stress in various tissues. Diazinon is mainly used in the agricultural field as an insecticide and may have potential effects on human and animal health[1][2][3][4].
PRICE
29
DESCRIPTION
Diazinon (Dimpylate) is a thiophosphoric acid ester, functioning as a nonsystemic organophosphate insecticide that effectively targets and controls a variety of pests including cockroaches, silverfish, ants, and fleas.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
9
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
37
Molecular Weight
304.1
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
0
Rotatable Bonds
7
Ring Count
1
Aromatic Ring Count
1
cLogP
3.58
TPSA
53.47
Fraction CSP3
0.67
Chiral centers
0.0
Largest ring
6.0
QED
0.72
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
AChE
Parasite
Indication
flea control
MOA
Acetylcholinesterase inhibitor
Pathway
Microbiology/virology
Neuroscience
Anti-infection
Source data
