General
Preferred name
INDOPROFEN
Synonyms
DEXINDOPROFEN ()
(¡À)-Indoprofe ()
(??)-Indoprofe ()
(±)-Indoprofe ()
Isindone ()
Reumofene ()
NSC-757065 ()
Praxis ()
Bor-ind ()
Flosin ()
K 4277 ()
K-4277 ()
Flosint ()
indoprofen ()
P&D ID
PD001930
CAS
31842-01-0
53022-60-9
Tags
natural product
drug
available
Drug indication
Analgesic
Gout
Anti-Inflammatory
Drug Status
approved
withdrawn
Max Phase
Phase 4
First approval
1979
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
16
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
26
Properties
(calculated by RDKit )
Molecular Weight
281.11
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
2
cLogP
3.04
TPSA
57.61
Fraction CSP3
0.18
Chiral centers
1.0
Largest ring
6.0
QED
0.94
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Immunology/Inflammation
Neuroscience
Target
COX
COX,Others,PDPK1
ATC
M01AE10
Toxicity type
carcinogenicity, gastrointestinal
Source data
