General
Preferred name
Diiodohydroxyquinoline
Synonyms
IODOQUINOL ()
5,7-Diiodo-8-hydroxyquinoline ()
5,7-Diiodo-8-quinolinol ()
Lanodoxin ()
Quinadome ()
NSC-8704 ()
SS-578 ()
Ioquin ()
Searlequin ()
Diiodohidroxiquinoleina ()
Enterodiamoebine ()
Diiodohydroxyquin ()
Zoaquin ()
Diiodohydroxyquinoleine ()
Diodoquin ()
Yodoxin ()
P&D ID
PD001928
CAS
83-73-8
Tags
available
drug
Approved by
FDA
Drug Status
approved
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Diiodohydroxyquinoline (Iodoquinol, 5,7-Diiodo-8-hydroxyquinoline, 5,7-Diiodo-8-quinolinol) has an orally active and satisfactory antiparasitic properties. Diiodohydroxyquinoline exhibits mutagenic potential in mice and potent anti-SARS-CoV-2 activity with an EC50 value of 1.38 ¦ÌM in VeroE6 cells. Diiodohydroxyquinoline's antimutagen is ascorbic acid. Diiodohydroxyquinoline is promising for research in inflammationin, testinal amebiasis, amebic liver abscess and chronic nonspecific diarrheas[1][2][3][4][5].
DESCRIPTION
Iodoquinol is a topical therapeutic agent, with satisfactory antibacterial properties.
(Enamine Bioactive Compounds)
DESCRIPTION
Diiodohydroxyquinoline (Iodoquinol), a topical therapeutic agent, has satisfactory antibacterial properties.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
2
Compound Sets
18
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
Enamine Bioactive Compounds
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Pathogen Box
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
33
Molecular Weight
396.85
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
2
Aromatic Ring Count
2
cLogP
3.15
TPSA
33.12
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.69
Structural alerts
2
aggregator (Aggregator Advisor)
Aggregators
aggregator (ZINC)
Aggregators
Related compounds
Custom attributes
(extracted from source data)
Disease
ONCHOCERCIASIS
Target
antibiotic
Bacterial
Parasite
SARS-CoV
MOA
Antibiotic
antiseptic
Indication
amebiasis
Pathway
Microbiology/virology
Anti-infection
Source data
