General
Preferred name
LEUCOVORIN CALCIUM
Synonyms
Folinic acid Calcium ()
Folinic acid calcium salt ()
Wellcovorin ()
Calcium folinate ()
Calcium leucovorin ()
Folinic acid (calcium) ()
Leucovorin (calcium) ()
Leucovorin calcium, Folinic acid calcium salt, Wellcovorin ()
Anhydrous calcium folinate ()
Calcium folinate pentahydrate ()
Calcii folinas ()
Citrovorum Factor ()
Rescufolin ()
Rescuvolin ()
Tonofolin ()
Folinic acid calcium salt pentahydrate ()
Leucovorin calcium preservative free ()
Lederfolat ()
Leucovorin Calcium Pentahydrate ()
NSC-3590 ()
Folinate-Sf Calcium ()
Folaren ()
Calc Folinate ()
Lederfolin ()
Folic acid related compound a ()
Leucosar ()
Folinic Acid ()
Foliben ()
Fusilev ()
Folacal ()
DL-Folinic Acid (calcium salt) ()
P&D ID
PD001918
CAS
1492-18-8
6035-45-6
Tags
natural product
drug
available
Drug indication
Antidote (to folic acid antagonists)
Anti-Anemic (folate deficiency)
Solid tumour/cancer
Drug Status
approved
Max Phase
Phase 4
First approval
1952
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Compound Sets
12
AdooQ Bioactive Compound Library
A11110
Cayman Chemical Bioactives
20383
ChEMBL Approved Drugs
CHEMBL1201138
ChEMBL Drugs
CHEMBL1201138
DrugMAP
DMNWZJG
DrugMAP Approved Drugs
DMNWZJG
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
HY-13664
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
calcium-folinate
TargetMol Bioactive Compound Library
T0148
The Spectrum Collection
External IDs
29
Properties
(calculated by RDKit )
Molecular Weight
511.11
Hydrogen Bond Acceptors
11
Hydrogen Bond Donors
5
Rotatable Bonds
10
Ring Count
3
Aromatic Ring Count
2
cLogP
-3.78
TPSA
225.5
Fraction CSP3
0.3
Chiral centers
2.0
Largest ring
6.0
QED
0.15
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
DNA Damage/DNA Repair
Metabolism
Cell Cycle/DNA Damage
Metabolic Enzyme/Protease
Target
Thymidylate Synthase
VB
Antifolate
Endogenous Metabolite
DHFR
MOA
DNA/RNA Synthesis inhibitor
Vitamin agonist
Therapeutic Class
Anticancer Agents
Source data