General
Preferred name
MEBHYDROLIN
Synonyms
Mebhydroline 1,5-naphthalenedisulfonate salt ()
Diazoline ()
Diazolin ()
Incidal ()
Omeril ()
Mebhydrolin napadisylate ()
Mebhydroline ()
Mebhydroline 1,5-naphtalenedisulfonate ()
Mebhydrolin (napadisylate) ()
Diazoline, Diazolin, Incidal, Omeril ()
Bexidal ()
Fabahistin ()
NSC-757830 ()
Mebhydrolin napadisilate ()
P&D ID
PD001894
CAS
524-81-2
6153-33-9
Tags
natural product
drug
available
First approval
1954
Drug Status
experimental
approved
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
16
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
Enamine BioReference Compounds
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
45
Properties
(calculated by RDKit )
Molecular Weight
276.16
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
3
cLogP
3.68
TPSA
8.17
Fraction CSP3
0.26
Chiral centers
0.0
Largest ring
6.0
QED
0.69
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Neuroscience
Immunology/Inflammation
Neuronal Signaling
Target
HT
mAChR
H1 receptor
Histamine Receptor
ADC Cytotoxin,Histamine Receptor
MOA
5-HT Receptor
AChR antagonist
antihistamine
Indication
allergic rhinitis, urticaria
Source data
