General
Preferred name
NEFOPAM
Synonyms
Fenazoxine hydrochloride ()
Nefopam HCl ()
NEFOPAM HYDROCHLORIDE ()
Acupan ()
NSC-757856 ()
(±)-Nefopam (hydrochloride) ()
P&D ID
PD001877
CAS
23327-57-3
13669-70-0
69319-31-9
Tags
available
drug
drug candidate
First approval
1978
Drug Status
approved
investigational
Max Phase
1.0
3.0
Drug indication
Pain
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
13
Cayman Chemical Bioactives
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
46
Molecular Weight
253.15
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
1
Ring Count
3
Aromatic Ring Count
2
cLogP
3.24
TPSA
12.47
Fraction CSP3
0.29
Chiral centers
1.0
Largest ring
8.0
QED
0.77
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
¦Â-catenin
Sodium Channel
β-catenin
??catenin
Pathway
Cytoskeletal Signaling
Membrane Transporter/Ion Channel
Stem Cells
Source data
