General
Preferred name
METHYLTHIOURACIL
Synonyms
MTU ()
NSC-193526 ()
NSC-9378 ()
NSC-193526, NSC-9378,MTU ()
Thimecil ()
P&D ID
PD001856
CAS
56-04-2
Tags
natural product
drug
available
Drug Status
experimental
approved
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Methylthiouracil is an antithyroid preparation.The drug acts to decrease the formation of stored thyroid hormone, as thyroglobulin in the thyroid gland.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
12
BOC Sciences Bioactive Compounds
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
NPC Screening Collection
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
33
Molecular Weight
142.02
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
1
Aromatic Ring Count
1
cLogP
0.74
TPSA
48.65
Fraction CSP3
0.2
Chiral centers
0.0
Largest ring
6.0
QED
0.52
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
NF-¦ÊB
antithyroid
ERK
Interleukin Related
TNF Receptor
ERK,Interleukins,NF-¦ÊB,TNF-alpha
Pathway
Immunology/Inflammation
NF-??
Apoptosis
MAPK/ERK Pathway
NF-κB
Stem Cell/Wnt
Indication
hyperthyroidism
Source data
