General
Preferred name
METRONIDAZOLE
Synonyms
Flagyl ()
Metronidazol ()
Anagiardil ()
METRONIDAZOLE HYDROCHLORIDE ()
RP 8823 ()
Flagyl Compak ()
Flagyl Er ()
BAYER-5360 ()
NSC-69587 ()
Flagyl 375 ()
Metro i.v. ()
Vaginyl ()
Metrogel ()
Flagyl-S ()
Metric 21 ()
Vandazole ()
Metrogel-Vaginal ()
Satric ()
Metrolyl ()
Metrocream ()
Metromidol ()
Gineflavir ()
Elyzol ()
Metrotop ()
Zyomet ()
Norzol ()
Deflamon ()
Zadstat ()
Rozex ()
Metrosa ()
Neutratop ()
BAY-5360 ()
RP-8823 ()
Flagyl-400 ()
Orvagil ()
NSC-50364 ()
Anabact ()
Noritate ()
Metrolotion ()
Drazifon ()
ACEA ()
Flagyl I.V. Rtu In Plastic Container ()
Rosiced ()
BAYER 5360 ()
Zidoval ()
Nuvessa ()
Protostat ()
SC-32642 ()
Metronidazole hcl ()
Flagyl I.V. ()
Metronidazole-d4 ()
P&D ID
PD001853
CAS
443-48-1
99616-64-5
69198-10-3
1261392-47-5
Tags
available
drug
Approved by
PMDA
FDA
First approval
1980
1963
Drug Status
approved
Drug indication
Antibacterial,Antiprotozoal (trichomonas)
Perianal crohn disease
Antibacterial
Crohn disease
Amoebiasis
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Metronidazole is a synthetic nitroimidazole derivative that exhibits antiprotozoal and antibacterial (against anaerobic bacteria) activities. It also acts as a a radiosensitising agent in tumour cells. (GtoPdb)
Cell lines
0
Organisms
6
Compound Sets
23
Cayman Chemical Bioactives
9002409
10010659
CeMM library of unique drugs (CLOUD)
ChEMBL Approved Drugs
CHEMBL137
CHEMBL1200869
ChEMBL Drugs
CHEMBL137
CHEMBL1200869
Drug Repurposing Hub
DrugBank
DB00916
DrugBank Approved Drugs
DB00916
DrugCentral
1790
DrugCentral Approved Drugs
1790
DrugMAP
DMTIVEN
DrugMAP Approved Drugs
DMTIVEN
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
10914
MedChem Express Bioactive Compound Library
HY-B0318
NCATS Inxight Approved Drugs
140QMO216E
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
Metronidazole(Flagyl)
TargetMol Bioactive Compound Library
T1079
The Spectrum Collection
External IDs
84
Properties
(calculated by RDKit )
Molecular Weight
171.06
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
0.09
TPSA
81.19
Fraction CSP3
0.5
Chiral centers
0.0
Largest ring
5.0
QED
0.52
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
bacterial DNA alkylator
DNA inhibitor
Target
DNA
14-?? Demethylase
Fe hydrogenase 1
NADPH nitroreductase
CYP2C9, CYP3A4
antibiotic
Bacterial
Parasite
Antineoplastic and Immunosuppressive Antibiotics,DNA/RNA Synthesis
Pathway
Metabolism
Microbiology&virology
Anti-infection
Apoptosis
Indication
rosacea
Therapeutic Class
Antiinfective Agents
Source data