General
Preferred name
METRONIDAZOLE
Synonyms
2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethan-1-ol ()
METRONIDAZOLE HYDROCHLORIDE ()
Metronidazole-d4 ()
Drazifon ()
Flagyl 375 ()
ACEA ()
RP-8823 ()
Zadstat ()
Metrosa ()
Metronidazol ()
Metrolyl ()
Metromidol ()
BAYER 5360 ()
Gineflavir ()
Satric ()
Flagyl-S ()
Rosiced ()
Noritate ()
BAYER-5360 ()
Metrogel-Vaginal ()
Metrogel ()
NSC-50364 ()
Metric 21 ()
Orvagil ()
Elyzol ()
Likmez ()
Vaginyl ()
Zidoval ()
BAY-5360 ()
Rozex ()
Flagyl Er ()
Metrocream ()
Flagyl-400 ()
Neutratop ()
Norzol ()
Nuvessa ()
Metronidazole component of pylera ()
Protostat ()
Deflamon ()
Vandazole ()
Flagyl Compak ()
Zyomet ()
Metrolotion ()
NSC-69587 ()
Metro iv ()
Metro i.v. ()
RP 8823 ()
Anabact ()
Metrotop ()
Flagyl ()
Metronidazole component of helidac ()
SC-32642 ()
Flagyl I.V. ()
Metronidazole hcl ()
P&D ID
PD001853
CAS
443-48-1
99616-64-5
69198-10-3
1261392-47-5
Tags
available
drug
Approved by
PMDA
FDA
First approval
1963
1980
Drug indication
infection
Amoebiasis
Perianal crohn disease
Crohn disease
Bacterial vaginosis
Drug Status
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Metronidazole is a synthetic nitroimidazole derivative that exhibits antiprotozoal and antibacterial (against anaerobic bacteria) activities. It also acts as a a radiosensitising agent in tumour cells. (GtoPdb)
DESCRIPTION Metronidazole is an orally active nitroimidazole antibiotic. Metronidazole can cross blood brain barrier. Metronidazole can be used for the research of anaerobic infections[1][2][3][4].
PRICE 29
DESCRIPTION Metronidazole (Metronidazol) is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
DESCRIPTION Metronidazole is an antibiotic that has activity against anaerobic bacteria and protozoa including T. vaginalis, E. histolytica, G. lamblia, C. difficile, and H. pylori. Metronidazole is indicated for the treatment of confirmed trichomoniasis caused by Trichomonas vaginalis, bacterial vaginosis, certain types of amebiasis, and various anaerobic infections. (Enamine Bioactive Compounds)
DESCRIPTION Antimicrobial activity against Trichomonas vaginalis G3 assessed as growth inhibition after 24 hrs by hemocytometry (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
6
Compound Sets
25
Cayman Chemical Bioactives
9002409
10010659
CeMM library of unique drugs (CLOUD)
ChEMBL Approved Drugs
CHEMBL137
CHEMBL1200869
ChEMBL Drugs
CHEMBL137
CHEMBL1200869
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DB00916
DrugBank Approved Drugs
DB00916
DrugCentral
1790
DrugCentral Approved Drugs
1790
DrugMAP
DMTIVEN
DrugMAP Approved Drugs
DMTIVEN
DrugMatrix
Enamine Bioactive Compounds
EBC-03271
Enamine BioReference Compounds
Guide to Pharmacology
10914
MedChem Express Bioactive Compound Library
HY-B0318
NCATS Inxight Approved Drugs
140QMO216E
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
Metronidazole(Flagyl)
TargetMol Bioactive Compound Library
8015-2129
The Spectrum Collection
External IDs
89
Properties
(calculated by RDKit )
Molecular Weight
171.06
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
0.09
TPSA
81.19
Fraction CSP3
0.5
Chiral centers
0.0
Largest ring
5.0
QED
0.52
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
bacterial DNA alkylator
DNA inhibitor
Target
DNA
CYP2C9, CYP3A4
antibiotic
Apoptosis
Bacterial
Parasite
Antineoplastic and Immunosuppressive Antibiotics,DNA/RNA Synthesis
Indication
rosacea
Therapeutic Class
Antiinfective Agents
Pathway
Anti-infection
Source data