General
Preferred name
OXYBENZONE
Synonyms
Hmbp cpd ()
Eusolex 4360 ()
Escalol 567 ()
Benzophenone 3 ()
Eusolex 4360, Escalol 567, KAHSCREEN BZ-3, Benzophenone 3 ()
2-Hydroxy-4-methoxybenzophenone ()
Oxibenzona ()
NSC-7778 ()
Ongrostab hmb ()
Advastab 45 ()
Oxybenzone component of shade uvaguard ()
Uvinul 40 ()
Viosorb 110 ()
Benzophenone-3 ()
Tinosorb b 3 ()
P&D ID
PD001821
CAS
131-57-7
Tags
available
drug
Approved by
FDA
First approval
1992
Drug indication
Discovery agent
freckles
Drug Status
approved
investigational
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells[1][2][3].
PRICE 29
DESCRIPTION Oxybenzone is a UV filter commonly used in tanning and skin protection agents. It is a derivative of benzophenone and is used as an endocrine disrupting chemical that penetrates the placental and blood-brain barriers. It impairs autophagy, alters epigenetic status and disrupts vitamin X-like receptor signaling in apoptotic neuronal cells.
DESCRIPTION 2-Hydroxy-4-methoxybenzophenone (benzophenone-3) is commonly employed as broad-band UV-filter in sunscreen cosmetic products. It protects skin from the deleterious effects of the sun. It is one of the sunscreen constituent and its trace determination in water samples by solid-phase microextraction (SPME) and gas chromatography with flame ionization and mass spectrometric detection has been reported. (BOC Sciences Bioactive Compounds)
DESCRIPTION Oxybenzone is a benzophenone derivative used as a sunscreen agent. Oxybenzone absorbs UV-A ultraviolet rays, preventing them from reaching the skin. (Enamine Bioactive Compounds)
Compound Sets
20
AdooQ Bioactive Compound Library
A16141
BOC Sciences Bioactive Compounds
2-hydroxy-4-methoxybenzophenone-cas-131-57-7-332344
Cayman Chemical Bioactives
42170
ChEMBL Approved Drugs
CHEMBL1625
ChEMBL Drugs
CHEMBL1625
Drug Repurposing Hub
DrugBank
DB01428
DrugBank Approved Drugs
DB01428
DrugCentral
3412
DrugCentral Approved Drugs
3412
DrugMAP
DMMZYX6
DrugMatrix
Enamine Bioactive Compounds
EBC-03702
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
HY-A0067
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
oxybenzone
The Spectrum Collection
External IDs
35
Properties
(calculated by RDKit )
Molecular Weight
228.08
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
2
cLogP
2.63
TPSA
46.53
Fraction CSP3
0.07
Chiral centers
0.0
Largest ring
6.0
QED
0.82
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
sunscreen lotion
Target
LIPE
Apoptosis
Autophagy
RAR/RXR
MOA
lipase inhibitor
Pathway
Metabolic Enzyme/Protease
Vitamin D Related/Nuclear Receptor
Source data