General
Preferred name
OXYBENZONE
Synonyms
Hmbp cpd ()
Eusolex 4360 ()
Escalol 567 ()
Benzophenone 3 ()
Eusolex 4360, Escalol 567, KAHSCREEN BZ-3, Benzophenone 3 ()
2-Hydroxy-4-methoxybenzophenone ()
Tinosorb b 3 ()
Benzophenone-3 ()
Ongrostab hmb ()
Advastab 45 ()
Uvinul M40 ()
Uvinul 40 ()
NSC-7778 ()
Viosorb 110 ()
P&D ID
PD001821
CAS
131-57-7
Tags
natural product
drug
available
Approved by
FDA
First approval
1992
Drug Status
investigational
approved
Drug indication
Discovery agent
Ultraviolet Screen
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 2-Hydroxy-4-methoxybenzophenone (benzophenone-3) is commonly employed as broad-band UV-filter in sunscreen cosmetic products. It protects skin from the deleterious effects of the sun. It is one of the sunscreen constituent and its trace determination in water samples by solid-phase microextraction (SPME) and gas chromatography with flame ionization and mass spectrometric detection has been reported. (BOC Sciences Bioactive Compounds)
Compound Sets
18
AdooQ Bioactive Compound Library
A16141
BOC Sciences Bioactive Compounds
2-hydroxy-4-methoxybenzophenone-cas-131-57-7-332344
ChEMBL Approved Drugs
CHEMBL1625
ChEMBL Drugs
CHEMBL1625
Drug Repurposing Hub
DrugBank
DB01428
DrugBank Approved Drugs
DB01428
DrugCentral
3412
DrugCentral Approved Drugs
3412
DrugMAP
DMMZYX6
DrugMatrix
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
HY-A0067
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
oxybenzone
The Spectrum Collection
External IDs
33
Properties
(calculated by RDKit )
Molecular Weight
228.08
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
2
cLogP
2.63
TPSA
46.53
Fraction CSP3
0.07
Chiral centers
0.0
Largest ring
6.0
QED
0.82
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
sunscreen lotion
Target
LIPE
RAR/RXR
MOA
lipase inhibitor
Pathway
Apoptosis
Autophagy
Metabolic Enzyme/Protease
Vitamin D Related/Nuclear Receptor
Source data