General
Preferred name
PHENYTOIN SODIUM
Synonyms
5,5-Diphenylhydantoin sodium salt ()
Diphenylhydantoin Sodium ()
Dilantin sodium ()
Diphantoine ()
Phenytoin sodium (Dilantin) ()
Phenytoin (sodium) ()
5,5-Diphenylhydantoin (sodium salt) ()
Aleviatin, Diphenylhydantoin sodium, Eptoin, Phenytoin soluble, Prompt,Phenytek,Dilantin sodium, Diphantoine ()
NSC-757274 ()
Dilantin ()
Diphenylan Sodium ()
Phenytek ()
Phenytoin sodium extended ()
Phenytoinum natricum ()
Phenytoin sodium,extended ()
Phenytoin sodium, extended ()
Prompt Phenytoin Sodium ()
Antisacer ()
Phenytoin sodium,prompt ()
Extended Phenytoin Sodium ()
Tacosal ()
Pentran ()
Phenytoin sodium for injection ()
Phenytex ()
Phenytoin sodium salt ()
Phenytoin sodium, prompt ()
P&D ID
PD001801
CAS
630-93-3
57-41-0
1421-15-4
Tags
natural product
drug
available
Drug Status
approved
Max Phase
Phase 4
Drug indication
Anticonvulsant
First approval
1956
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Anticonvulsant; anti-epileptic (LOPAC library)
DESCRIPTION Phenytoin Sodium is a potent multi-channel blocker, which blocks Na+, K+ and Ca 2+ channels and selectively blocks persistent INaP over shorter INaP actions. (BOC Sciences Bioactive Compounds)
Compound Sets
10
AdooQ Bioactive Compound Library
A10722
BOC Sciences Bioactive Compounds
phenytoin-sodium-cas-630-93-3-item-84-180245
ChEMBL Approved Drugs
CHEMBL1611
ChEMBL Drugs
CHEMBL1611
LOPAC library
MedChem Express Bioactive Compound Library
HY-B0448A
NIH Clinical Collections (NCC)
Selleckchem Bioactive Compound Library
Phenytoin-sodium-Dilantin
TargetMol Bioactive Compound Library
T0008
The Spectrum Collection
External IDs
30
Properties
(calculated by RDKit )
Molecular Weight
274.07
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
2
cLogP
-0.44
TPSA
60.27
Fraction CSP3
0.07
Chiral centers
0.0
Largest ring
6.0
QED
0.6
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Membrane Transporter/Ion Channel
Anti-infection
Target
Sodium Channel
Virus Protease
MOA
Sodium Channel inhibitor
Source data