General
Preferred name
PIPERAZINE
Synonyms
Piperazine Hexahydrate ()
Diethylenediamine ()
exahydropyrazine ()
Piperazidine ()
1,4-Diazacyclohexane ()
NSC-474 ()
Ascalix ()
Antepar ()
Ectodyne ()
Ins Umuline Rapide ()
FEMA NO. 4250 ()
Wormex ()
Expelix ()
P02CB01 ()
P&D ID
PD001796
CAS
110-85-0
41372-10-5
142-63-2
144-29-6
Tags
available
drug
Approved by
FDA
First approval
1954
Drug indication
Helminthiasis
Enterobiasis
Ascariasis
Drug Status
vet_approved
approved
withdrawn
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
18
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
CeMM library of unique drugs (CLOUD)
ChEMBL Approved Drugs
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Enamine BioReference Compounds
NPC Screening Collection
ReFrame library
The Spectrum Collection
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
48
Properties
(calculated by RDKit )
Molecular Weight
86.08
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
1
Aromatic Ring Count
0
cLogP
-0.82
TPSA
24.06
Fraction CSP3
1.0
Chiral centers
0.0
Largest ring
6.0
QED
0.4
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
metabotropic GABA receptor agonist
benzodiazepine receptor agonist
Target
Nematode GABA-A receptor
GABRB3
Indication
gastrointestinal roundworms
ATC
P02CB01
Toxicity type
carcinogenicity
Therapeutic Class
Antinematodal Agents
Source data
