General
Preferred name
PRIMAQUINE PHOSPHATE
Synonyms
Primaquine bisphosphate ()
Primaquine Diphosphate ()
Primaquine (Diphosphate) ()
Primaquine (phosphate) ()
Primaquine (bisphosphate) ()
Primaquine diphosphate ()
NSC-149765 ()
Malquine ()
Primachine phosphate ()
Primaquine ()
Primaquini diphosphas ()
WR 2975 ()
P&D ID
PD001788
CAS
90-34-6
63-45-6
Tags
natural product
drug
available
Drug Status
approved
Max Phase
Phase 4
Drug indication
Antimalarial
First approval
1952
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Primaquine is the only generally available anti-malarial that prevents relapse in vivax and ovale malaria, and the only potent gametocytocide in falciparum malaria. (BOC Sciences Bioactive Compounds)
Cell lines
10
Organisms
2
Compound Sets
10
Axon Medchem Screening Library
3177
BOC Sciences Bioactive Compounds
primaquine-bisphosphate-cas-63-45-6-74002
Cayman Chemical Bioactives
18223
ChEMBL Approved Drugs
CHEMBL43128
ChEMBL Drugs
CHEMBL43128
MedChem Express Bioactive Compound Library
HY-12651
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
primaquine-diphosphate
TargetMol Bioactive Compound Library
T0850
The Spectrum Collection
External IDs
16
Properties
(calculated by RDKit )
Molecular Weight
455.12
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
8
Rotatable Bonds
6
Ring Count
2
Aromatic Ring Count
2
cLogP
0.93
TPSA
215.69
Fraction CSP3
0.4
Chiral centers
1.0
Largest ring
6.0
QED
0.29
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology&virology
Anti-infection
Target
antibiotic
Antimalarial drug
Parasite
MOA
Antibiotic
Source data