General
Preferred name
PROCAINAMIDE HYDROCHLORIDE
Synonyms
Procainamide HCl ()
Pronestyl ()
Procanbid ()
Procapan ()
Procainamide (hydrochloride) ()
Procainamidi hydrochloridum ()
Pronestyl-SR ()
Biocoryl ()
Procan sr ()
Novocainamid ()
Cardiorytmin ()
Procan ()
NSC-757279 ()
Amidoprocaine ()
P&D ID
PD001785
CAS
614-39-1
Tags
natural product
drug
available
Drug Status
approved
Max Phase
Phase 4
Drug indication
Cardiac Depressant (anti-arrhythmic)
First approval
1950
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Na+ channel blocker and Class I anti-arrhythmic (LOPAC library)
Compound Sets
11
Cayman Chemical Bioactives
24359
ChEMBL Approved Drugs
CHEMBL605
ChEMBL Drugs
CHEMBL605
Enamine BioReference Compounds
LOPAC library
MedChem Express Bioactive Compound Library
HY-A0084
NIH Clinical Collections (NCC)
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
procainamide-hcl
TargetMol Bioactive Compound Library
T0018
The Spectrum Collection
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
271.15
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
6
Ring Count
1
Aromatic Ring Count
1
cLogP
1.76
TPSA
58.36
Fraction CSP3
0.46
Chiral centers
0.0
Largest ring
6.0
QED
0.78
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Chromatin/Epigenetic
Membrane Transporter/Ion Channel
Neuroscience
Autophagy
Target
AChR
DNA (cytosine-5)-methyltransferase 1
Sodium Channel
DNA Methyltransferase,Sodium Channel
Source data