General
Preferred name
PROCAINE HYDROCHLORIDE
Synonyms
Procaine HCl ()
Novocaine HCl ()
Procaine (hydrochloride) ()
Procaini hydrochloridum ()
Jenacaine ()
Syntocain ()
Rocain ()
SP-01A ()
Neocaine ()
Sp01a ()
NSC-757280 ()
Novocain ()
Anestil ()
Omnicain ()
Enpro ()
Planocaine ()
Pasconeural N ()
Medaject ()
Naucaine ()
Procaine (hydrochloride) ()
P&D ID
PD001784
CAS
51-05-8
59-46-1
12663-50-2
Tags
natural product
drug
available
Drug Status
approved
Max Phase
Phase 4
Drug indication
Anesthetic (local)
First approval
1954
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Na+ channel blocker
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Enamine BioReference Compounds
LOPAC library
MedChem Express Bioactive Compound Library
NIH Clinical Collections (NCC)
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
29
Molecular Weight
272.13
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
6
Ring Count
1
Aromatic Ring Count
1
cLogP
2.19
TPSA
55.56
Fraction CSP3
0.46
Chiral centers
0.0
Largest ring
6.0
QED
0.64
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Membrane Transporter/Ion Channel
Neuroscience
Anti-infection
Cell Cycle/DNA Damage
Epigenetics
Target
5-HT3
nAChR
NMDA Receptor
Sodium Channel
Bacterial
DNA/RNA Synthesis
Histone Demethylase
AChR,NMDAR,Sodium Channel
Source data
