General
Preferred name
SULFAMETHAZINE
Synonyms
SULFAMERAZINE ()
Sulfadimethyldiazine Sodium Salt ()
Sulfamethazine sodium salt ()
sulfadimidine ()
Sulfamethazine ()
Sulfamethazine (sodium) ()
Sulfadimerazine ()
Sulfadimidine (sodium) ()
Sulfadimerazine (sodium) ()
Sulfadimidine,Sulfadimerazine ()
Sulfamethazine sodium ()
4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzene-1-sulfonamide ()
Sulfadimethylpyrimidine ()
Sulfadimidinum ()
Sulfamidine ()
NSC-67457 ()
NSC-683529 ()
Sulfamethazine (trisulfapyrimidines) component of neotrizine ()
Sulfadimidina ()
Sulfamethazine (trisulfapyrimidines) component of terfonyl ()
Sulfamezathine ('S-Mez') ()
Trisulfapyrimidines (sulfamethazine) ()
Sulphadimidine ()
Smz-Med 454 ()
Sulfamethazine (trisulfapyrimidines) ()
Sulfamethazine component of sulfose ()
Sulfamethazine component of terfonyl ()
Sulfamethazine component of lantrisul ()
Sulfamezathine ()
BN-2409 ()
Sulfamethazine component of triple sulfoid ()
Sulfamethazine component of neotrizine ()
Sulfamethazine component of sulfaloid ()
Sulfamethazine-d4 ()
P&D ID
PD001748
CAS
57-68-1
1981-58-4
1020719-82-7
Tags
available
drug
Approved by
FDA
First approval
1949
Drug indication
bacterial disease
Bacterial infection
Drug Status
vet_approved
approved
withdrawn
investigational
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Sulfadimidine (sulfamethazine) is a sulfonamide antibacterial compound. This class of compounds are competitive inhibitors of bacterial dihydropteroate synthase (DHPS), an enzyme in the pathway which generates the folic acid that is essential for bacterial growth. (GtoPdb)
DESCRIPTION Sulfamethazine (Sulfadimidine) is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections). In China and the European Commission, the maximum residue level for Sulfamethazine in animal product is set at 100 ¦Ìg/kg[1][2].
PRICE 29
DESCRIPTION Sulfamethazine (Sulfadimidine) is a sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.
DESCRIPTION Sulfamethazine sodium (Sulfadimidine sodium) is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections). In China and the European Commission, the maximum residue level for Sulfamethazine sodium in animal product is set at 100 ¦Ìg/kg[1][2].
PRICE 29
DESCRIPTION Sulfamethazine is an antibacterial sulfonamide. Sulfamethazine inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydrofolate synthetase. It is used for the treatment bacterial infections causing bronchitis, prostatitis and urinary tract infections. (Enamine Bioactive Compounds)
DESCRIPTION PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of androgen receptor signaling. (Class of assay: confirmatory) (TargetMol Bioactive Compound Library)
DESCRIPTION Sulfamethazine sodium (Sulfadimethyldiazine Sodium Salt) salt is a sodium salt form of sulfamethazine, a sulfonamide antibiotic used in the livestock industry. (TargetMol Bioactive Compound Library)
Compound Sets
23
Cayman Chemical Bioactives
20976
36575
ChEMBL Approved Drugs
CHEMBL446
ChEMBL Drugs
CHEMBL446
Drug Repurposing Hub
DrugBank
DB01582
DrugBank Approved Drugs
DB01582
DrugCentral
2502
DrugCentral Approved Drugs
2502
DrugMAP
DMRGZ16
DrugMAP Approved Drugs
DMRGZ16
DrugMatrix
Enamine Bioactive Compounds
EBC-03813
Enamine BioReference Compounds
Guide to Pharmacology
12642
MedChem Express Bioactive Compound Library
HY-B0035
HY-B0035A
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
sulfamethazine
sulfamethazine-sodium-salt
TargetMol Bioactive Compound Library
0519-0281
T2184L
The Spectrum Collection
Withdrawn 2.0
56
External IDs
67
Properties
(calculated by RDKit )
Molecular Weight
278.08
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
2
cLogP
1.48
TPSA
97.97
Fraction CSP3
0.17
Chiral centers
0.0
Largest ring
6.0
QED
0.83
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
antibiotic
Bacterial
MOA
Antibiotic
PABA antagonist
Pathway
Microbiology&virology
Microbiology/virology
Anti-infection
Indication
enteritis
ATC
J01EB03
Therapeutic Class
Antiinfective Agents
Source data