General
Preferred name
SULFAMETHIZOLE
Synonyms
Sulfamethizol ()
Tetracid ()
NSC-757327 ()
Methazol ()
Microsul ()
Sulphamethylthiadiazole ()
Urolucosil ()
Thiosulfil ()
Sulphamethizole ()
Proklar ()
Sulfamethizole-d4 ()
P&D ID
PD001747
CAS
144-82-1
2470130-12-0
Tags
natural product
drug
available
Approved by
FDA
First approval
1953
Drug Status
investigational
withdrawn
approved
vet_approved
Drug indication
Antibacterial
Urinary tract infection
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Sulfamethizole is an orally available sulfonamide antibacterial compound. (GtoPdb)
Compound Sets
21
Cayman Chemical Bioactives
23355
26789
ChEMBL Approved Drugs
CHEMBL1191
ChEMBL Drugs
CHEMBL1191
Drug Repurposing Hub
DrugBank
DB00576
DrugBank Approved Drugs
DB00576
DrugCentral
2512
DrugCentral Approved Drugs
2512
DrugMAP
DMGCHDS
DrugMAP Approved Drugs
DMGCHDS
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
12683
MedChem Express Bioactive Compound Library
HY-B0333
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
Sulfamethizole(Proklar)
TargetMol Bioactive Compound Library
T0754
The Spectrum Collection
Withdrawn 2.0
w142
External IDs
39
Properties
(calculated by RDKit )
Molecular Weight
270.02
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
2
cLogP
1.23
TPSA
97.97
Fraction CSP3
0.11
Chiral centers
0.0
Largest ring
6.0
QED
0.82
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
PD-1/PD-L1
DHPS
antibiotic
Bacterial
Pathway
Immunology/Inflammation
Autophagy
Anti-infection
Indication
urinary tract infections
MOA
bacterial antifolate
ATC
B05CA04
D06BA04
J01EB02
S01AB01
Therapeutic Class
Antiinfective Agents
Source data