General
Preferred name
SULFATHIAZOLE
Synonyms
SULFACETAMIDE ()
2-Sulfanilamidothiazole ()
Triple sulfa (sulfathiazole) ()
Sulfathiazole (Triple Sulfa) ()
Thiazamide ()
Sulphathiazole ()
NSC-683531 ()
NSC-31812 ()
P&D ID
PD001743
CAS
72-14-0
158269-46-6
Tags
natural product
drug
available
Approved by
FDA
First approval
1945
Drug Status
withdrawn
approved
vet_approved
Max Phase
Phase 4
Drug indication
Antibacterial
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Sulfathiazole is a sulfonamide antibacterial compound . (GtoPdb)
DESCRIPTION Sulfathiazole is an organosulfur compound that has been used as a short-acting sulfa drug. It can be mainly used for the treatment of digestive tract, respiratory tract infections, mastitis, endometritis and other diseases caused by sensitive bacteria in domestic animals, and it can also be used for toxoplasma infection. (BOC Sciences Bioactive Compounds)
Cell lines
1
Organisms
1
Compound Sets
20
BOC Sciences Bioactive Compounds
sulfathiazole-cas-72-14-0-75917
ChEMBL Approved Drugs
CHEMBL437
ChEMBL Drugs
CHEMBL437
Drug Repurposing Hub
DrugBank
DB06147
DrugBank Approved Drugs
DB06147
DrugCentral
2527
DrugCentral Approved Drugs
2527
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
12699
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL437
MedChem Express Bioactive Compound Library
HY-B0507
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
sulfathiazole
TargetMol Bioactive Compound Library
T0747
The Spectrum Collection
Withdrawn 2.0
w67
External IDs
35
Properties
(calculated by RDKit )
Molecular Weight
255.01
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
2
cLogP
1.53
TPSA
85.08
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.81
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Autophagy
Anti-infection
Target
DHPS
antibiotic
Bacterial
Indication
gram-negative bacterial infections, gram-positive bacterial infections
MOA
dihydropteroate synthase inhibitor
ATC
D06BA02
J01EB07
Toxicity type
hepatic
Source data