General
Preferred name
SULFISOXAZOLE
Synonyms
sulfafurazole ()
NU-445 ()
Sulfisoxazole127-69-5 ()
SULFISOXAZOLE DIOLAMINE ()
Sosol ()
NSC-683536 ()
Pediazole ()
Soxazole ()
Sulfalar ()
Neazolin ()
Entusil ()
Sulphafurazole ()
Eryzole ()
Gantrisin ()
Sulsoxin ()
NSC-13120 ()
Sulfafurazole diolamine ()
Sulfisoxazole diethanolamine salt ()
Sulfafurazole diethanolamine ()
Sulphafurazole diolamine ()
P&D ID
PD001741
CAS
127-69-5
4299-60-9
Tags
natural product
drug
available
Approved by
FDA
First approval
1982
1971
Drug Status
withdrawn
approved
vet_approved
Drug indication
Antibacterial
Urinary tract infection
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Sulfisoxazole (sulfafurazole) is a sulfonamide antibacterial compound .
(GtoPdb)
DESCRIPTION
Endothelin ETA antagonist
(Tocriscreen Total)
DESCRIPTION
Sulfisoxazole is a sulfonamide antibacterial with an oxazole substituent.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
27
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
Mcule NIBR MoA Box Subset
MedChem Express Bioactive Compound Library
NIH Clinical Collections (NCC)
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
Tocriscreen Total
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
50
Molecular Weight
267.07
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
2
cLogP
1.67
TPSA
98.22
Fraction CSP3
0.18
Chiral centers
0.0
Largest ring
6.0
QED
0.82
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Autophagy
Anti-infection
GPCR/G protein
Target
DHPS
antibiotic
Bacterial
Endothelin Receptor
Member status
member
MOA
Endothelin Receptor Antagonists
bacterial antifolate
Indication
urinary tract infections
ATC
J01EB05
S01AB02
Therapeutic Class
Antiinfective Agents
Source data
