General
Preferred name
TRIACETIN
Synonyms
1,2,3-Propanetriol, triacetate ()
Glycerol triacetate ()
1,2,3-Triacetoxypropane ()
Glyceryl triacetate ()
Glycerin triacetate ()
Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane ()
Glyceryltriacetate ()
Estol 1581 ()
Triacetina ()
E1518 ()
Ujostabil ()
Ins no.1518 ()
Triacetine ()
E-1518 ()
NSC-4796 ()
Ins-1518 ()
FEMA NO. 2007 ()
Enzactin ()
P&D ID
PD001722
CAS
102-76-1
Tags
available
drug
Drug indication
Onychomycosis
Canavan disease
Drug Status
approved
experimental
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Triacetin (Glyceryl triacetate) is a synthetic compound that is a triester of glycerol and acetic acid, orally active. Triacetin increases acetate bioavailability in glioma cells. Triacetin induces glioma cell growth arrest and Apoptosis. Triacetin freely crosses the blood brain barrier/plasma membrane. Triacetin increases histone acetylation and enhances Temozolomide (HY-17364) (TMZ) chemotherapeutic efficacy [1][2].
PRICE
29
DESCRIPTION
Triacetin (Glyceryl triacetate) is a triglyceride that is used as an antifungal agent.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
14
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
40
Molecular Weight
218.08
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
0
Rotatable Bonds
5
Ring Count
0
Aromatic Ring Count
0
cLogP
0.04
TPSA
78.9
Fraction CSP3
0.67
Chiral centers
0.0
Largest ring
0.0
QED
0.48
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolism
Microbiology/virology
Cell Cycle/DNA Damage
Epigenetics
Target
Apoptosis
HDAC
Fungal
Antifungal
Endogenous Metabolite
Source data
